⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16433889 | 0.77 | — | — | |
| SCHEMBL12315016 | 0.75 | ALDH1A1 (0.38) | — | |
| SCHEMBL3409151 | 0.75 | CHRM5 (0.68) | — | |
| SCHEMBL3416208 | 0.73 | CHRM5 (0.58) | — | |
| Methyl Alcohol SCHEMBL28737572 | 0.73 | CHRM5 (0.57) | — | |
| SCHEMBL10874328 | 0.73 | CHRM5 (0.94) | — | |
| SCHEMBL11968930 | 0.71 | CHRM5 (0.55) | — | |
| SCHEMBL6325002 | 0.71 | CHRM5 (0.42) | — | |
| SCHEMBL27695417 | 0.71 | CHRM5 (0.42) | — | |
| SCHEMBL20628911 | 0.69 | CHRM5 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11807641-B2 | MASP-2 inhibitors and methods of use | OMEROS CORPORATION (US) | 2023-11-07 | — | — | US | disclosed |
| US-11807641-B2 | MASP-2 inhibitors and methods of use | OMEROS CORPORATION (US) | 2023-11-07 | — | — | US | disclosed |
| US-20230321050-A1 | Heterocyclic Compounds and Uses Thereof | MILLENNIUM PHARMACEUTICALS, INC. | 2023-10-12 | — | — | US | disclosed |
| US-20230321050-A1 | Heterocyclic Compounds and Uses Thereof | MILLENNIUM PHARMACEUTICALS, INC. | 2023-10-12 | — | — | US | disclosed |
| US-11547697-B2 | Heterocyclic compounds and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2023-01-10 | — | — | US | disclosed |
| US-20210171531-A1 | MASP-2 INHIBITORS AND METHODS OF USE | OMEROS CORPORATION | 2021-06-10 | — | — | US | disclosed |
| CN-111378138-A | Combined energy absorption method and application thereof | 翁秋梅 | 2020-07-07 | — | — | CN | disclosed |
| CN-111378137-A | Force-induced responsive polymer with multi-network structure | 翁秋梅 | 2020-07-07 | — | — | CN | disclosed |
| CN-111253610-A | Dynamic polymer foam composite material | 翁秋梅 | 2020-06-09 | — | — | CN | disclosed |
| CN-111150173-A | Shock attenuation sole and shock attenuation shoes | 翁秋梅 | 2020-05-15 | — | — | CN | disclosed |
| CN-111040202-A | Combined hybrid dynamic polymer and application thereof | 翁秋梅 | 2020-04-21 | — | — | CN | disclosed |
| US-20190350906-A1 | Heterocyclic Compounds and Uses Thereof | INTELLIKINE, LLC | 2019-11-21 | — | — | US | disclosed |
| US-20180042902-A1 | Heterocyclic Compounds and Uses Thereof | INTELLIKINE, LLC | 2018-02-15 | — | — | US | disclosed |
| US-20180042902-A1 | Heterocyclic Compounds and Uses Thereof | INTELLIKINE, LLC | 2018-02-15 | — | — | US | disclosed |