Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 3/20 | 0.38 |
| ▸ | BACE1 | P56817 | 3/20 | 0.38 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19863729 | 0.96 | ESR1 (0.58) | ESR1ESR2PPARAACHEALOX15 | |
| SCHEMBL17523062 | 0.95 | ESR1 (0.59) | ESR1ESR2PPARAACHEALOX15 | |
| SCHEMBL25620272 | 0.95 | ESR1 (0.59) | ESR1ESR2PPARAACHEALOX15 | |
| SCHEMBL19268516 | 0.95 | ESR1 (0.59) | ESR1ESR2PPARAACHEALOX15 | |
| SCHEMBL13892815 | 0.86 | ESR1 (0.77) | ESR1ESR2PPARAACHEALOX15 | |
| SCHEMBL28232465 | 0.85 | LMNA (0.54) | ESR1ESR2ACHELMNAALDH1A1 | |
| SCHEMBL17084644 | 0.83 | PPARA (0.52) | ESR1ESR2PPARAACHELMNA | |
| SCHEMBL13054815 | 0.83 | PPARA (0.49) | ESR1ESR2PPARAACHEALOX15 | |
| SCHEMBL26009186 | 0.82 | PPARA (0.54) | ESR1ESR2PPARAACHELMNA | |
| SCHEMBL26009188 | 0.82 | PPARA (0.54) | ESR1ESR2PPARAACHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180046099-A1 | POLYARYLATE RESIN AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2018-02-15 | — | — | US | disclosed |
| US-20180046100-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2018-02-15 | — | — | US | disclosed |
| US-20180046101-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2018-02-15 | — | — | US | disclosed |