Sugi Predict

Sugi Predict / Compounds / SCHEMBL19863497

SCHEMBL19863497

SCHEMBL19863497

COc1ccc(C2(c3ccc(OC(=O)c4ccc5cc(C(=O)Oc6ccc(C7(c8ccc(OC(=O)c9ccc(-c%10ccc(C(C)=O)cc%10)cc9)c(C)c8)CCCCC7)cc6C)ccc5c4)c(C)c3)CCCCC2)cc1C

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ RARA P10276 1/20 0.43
▸ RARB P10826 1/20 0.43
▸ RARG P13631 1/20 0.43
▸ PPARA Q07869 1/20 0.42
▸ KMT2A Q03164 6/20 0.38
▸ MAPT P10636 4/20 0.38
▸ GAA P10253 1/20 0.38
▸ NR1H4 Q96RI1 1/20 0.38
▸ ESR1 P03372 2/20 0.38
▸ ESR2 Q92731 2/20 0.38
▸ LMNA P02545 1/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ ALDH1A1 P00352 4/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ HDAC1 Q13547 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19870997 0.98 RARA (0.43) RARARARBRARGPPARAKMT2A
SCHEMBL19870993 0.95 PPARA (0.46) RARARARBRARGPPARAKMT2A
SCHEMBL26431895 0.94 PPARA (0.45) RARARARBRARGPPARAKMT2A
SCHEMBL19863501 0.93 PPARA (0.41) RARARARBRARGPPARAKMT2A
SCHEMBL19870999 0.93 PPARA (0.41) RARARARBRARGPPARAKMT2A
SCHEMBL19870994 0.93 PPARA (0.41) RARARARBRARGPPARAKMT2A
SCHEMBL19870998 0.92 KMT2A (0.41) RARARARBRARGPPARAKMT2A
SCHEMBL19863499 0.92 PPARA (0.42) RARARARBRARGPPARAKMT2A
SCHEMBL12762427 0.92 PPARA (0.48) RARARARBRARGPPARAKMT2A
SCHEMBL19863500 0.91 PPARA (0.41) RARARARBRARGPPARAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180046099-A1 POLYARYLATE RESIN AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2018-02-15 — — US disclosed
US-20180046098-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2018-02-15 — — US disclosed
US-20180046101-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2018-02-15 — — US disclosed
US-20180046100-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2018-02-15 — — US disclosed