SCHEMBL19863540

SCHEMBL19863540

c1ccc2c(c1)c1ccccc1n2-c1ccc(-n2c3ccccc3c3c2ccc2c4ccccc4n(-c4ccc(-n5c6ccccc6c6ccccc65)cc4)c23)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.55
ATM Q13315 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
PTPN1 P18031 2/20 0.35
HDAC4 P56524 1/20 0.35
GPR3 P46089 1/20 0.34
ALKBH5 Q6P6C2 1/20 0.34
FTO Q9C0B1 1/20 0.34
DUSP3 P51452 1/20 0.34
JAK2 O60674 1/20 0.33
JAK3 P52333 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
MAPT P10636 1/20 0.33
POLB P06746 1/20 0.33
GABRP O00591 1/20 0.33
GABRD O14764 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRB1 P18505 1/20 0.33
GABRG2 P18507 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12691126 0.96 L3MBTL1 (0.62) KDM4EATML3MBTL1PTPN1HDAC4
SCHEMBL10027641 0.96 L3MBTL1 (0.62) KDM4EATML3MBTL1PTPN1HDAC4
SCHEMBL10027526 0.96 L3MBTL1 (0.62) KDM4EATML3MBTL1PTPN1HDAC4
SCHEMBL17245455 0.96 L3MBTL1 (0.62) KDM4EATML3MBTL1PTPN1HDAC4
SCHEMBL26060236 0.96 L3MBTL1 (0.62) KDM4EATML3MBTL1PTPN1HDAC4
SCHEMBL31744513 0.96 L3MBTL1 (0.62) KDM4EATML3MBTL1PTPN1HDAC4
SCHEMBL19849224 0.95 L3MBTL1 (0.60) KDM4EATML3MBTL1PTPN1HDAC4
SCHEMBL12456509 0.95 L3MBTL1 (0.60) KDM4EATML3MBTL1PTPN1HDAC4
SCHEMBL30092608 0.95 L3MBTL1 (0.64) KDM4EATML3MBTL1PTPN1JAK2
SCHEMBL4378079 0.95 L3MBTL1 (0.64) KDM4EATML3MBTL1PTPN1JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10600971-B2 Composition for organic optoelectric device and organic optoelectric device and display device SAMSUNG SDI CO., LTD. (KR) 2020-03-24 US disclosed
US-20180047916-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-02-15 US disclosed
US-20180047916-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10600971-B2 Composition for organic optoelectric device and organic optoelectric device and display device OXER1, OR10J3, OR51E2 KDM4E 4718/4885ATM 4443/4885L3MBTL1 4752/4885
US-20180047916-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE OXER1, OR10J3, OR51E2 KDM4E 4718/4885ATM 4443/4885L3MBTL1 4752/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.