SCHEMBL19864293

SCHEMBL19864293

Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(C[C@@H](O)[C@@H](O)[C@@H](O)COP(C)(=O)O)c2cc1C

nearest known ligand 0.88

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.88
NR3C1 P04150 1/20 0.88
ADRB2 P07550 1/20 0.88
HTR2C P28335 1/20 0.88
ADRA1A P35348 1/20 0.88
PTGS2 P35354 1/20 0.88
TST Q16762 2/20 0.82
HSPD1 P10809 1/20 0.82
HSPE1 P61604 1/20 0.82
MEN1 O00255 7/20 0.72
KMT2A Q03164 7/20 0.72
USP2 O75604 4/20 0.72
HTT P42858 4/20 0.72
KDM4E B2RXH2 4/20 0.72
HAT1 O14929 4/20 0.72
RBBP7 Q16576 4/20 0.72
RECQL P46063 3/20 0.72
CASP7 P55210 3/20 0.72
MAPT P10636 3/20 0.72
CASP1 P29466 2/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11995383 1.00 ESR1 (0.88) ESR1NR3C1ADRB2HTR2CADRA1A
Riboflavin 5'-Phosphate SCHEMBL1532396 0.94 ESR1 (1.00) ESR1NR3C1ADRB2HTR2CADRA1A
Riboflavin 5'-Phosphate SCHEMBL297863 0.94 ESR1 (1.00) ESR1NR3C1ADRB2HTR2CADRA1A
Riboflavin 5'-Phosphate SCHEMBL190079 0.94 ESR1 (1.00) ESR1NR3C1ADRB2HTR2CADRA1A
Riboflavin 5'-Phosphate SCHEMBL41133 0.94 ESR1 (1.00) ESR1NR3C1ADRB2HTR2CADRA1A
Riboflavin 5'-Phosphate SCHEMBL6681480 0.93 ESR1 (0.98) ESR1NR3C1ADRB2HTR2CADRA1A
SCHEMBL10253828 0.91 ESR1 (0.74) ESR1NR3C1ADRB2HTR2CADRA1A
Riboflavin 5'-Phosphate SCHEMBL26122 0.91 TST (0.98) ESR1NR3C1ADRB2HTR2CADRA1A
Riboflavin 5'-Phosphate SCHEMBL623880 0.91 TST (0.98) ESR1NR3C1ADRB2HTR2CADRA1A
Riboflavin 5'-Phosphate SCHEMBL8656633 0.91 TST (0.98) ESR1NR3C1ADRB2HTR2CADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180048011-A1 HIGH pH ORGANIC FLOW BATTERY U.S. DEPARTMENT OF ENERGY 2018-02-15 US disclosed