SCHEMBL19864591

SCHEMBL19864591

CC1(C)CCCCCC(C)(C#N)CCCC1

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
PDE4A P27815 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14533550 0.92 ALDH1A1 (0.52) ALDH1A1PDE4A
SCHEMBL12360987 0.92 ALDH1A1 (0.52) ALDH1A1PDE4A
SCHEMBL10029791 0.92 ALDH1A1 (0.52) ALDH1A1PDE4A
SCHEMBL5125852 0.92 ALDH1A1 (0.52) ALDH1A1PDE4A
SCHEMBL12866832 0.92 ALDH1A1 (0.52) ALDH1A1PDE4A
SCHEMBL860505 0.92
SCHEMBL16137665 0.92 ALDH1A1 (0.52) ALDH1A1PDE4A
SCHEMBL1928641 0.89
SCHEMBL1930515 0.83
SCHEMBL24473252 0.80 ALDH1A1 (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018030550-A1 HETEROCYCLIC COMPOUNDS WITH AN ROR(GAMMA)T MODULATING ACTIVITY TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2018-02-15 WO disclosed