⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL734381 | 0.89 | — | — | |
| SCHEMBL1986486 | 0.63 | — | — | |
| SCHEMBL8473442 | 0.60 | — | — | |
| Boric Acid SCHEMBL29941576 | 0.59 | — | — | |
| Boric Acid SCHEMBL30628544 | 0.59 | LMNA (0.57) | — | |
| Ethane SCHEMBL2138018 | 0.53 | — | — | |
| SCHEMBL25228156 | 0.52 | — | — | |
| SCHEMBL1276 | 0.52 | — | — | |
| SCHEMBL2496497 | 0.52 | — | — | |
| SCHEMBL12054244 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2146986-B1 | DIPHENYL-DIHYDRO-IMIDAZOPYRIDINONES | HOFFMANN LA ROCHE (CH) | 2011-06-29 | — | — | EP | disclosed |
| EP-2146986-A1 | DIPHENYL-DIHYDRO-IMIDAZOPYRIDINONES | F. Hoffmann-Roche AG (CH) | 2010-01-27 | — | — | EP | disclosed |
| US-7625895-B2 | Diphenyl-dihydro-imidazopyridinones | Hoffmann-Le Roche Inc. (US) | 2009-12-01 | — | — | US | disclosed |
| WO-2008125487-A1 | DIPHENYL-DIHYDRO-IMIDAZOPYRIDINONES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-10-23 | — | — | WO | disclosed |
| US-20080255119-A1 | DIPHENYL-DIHYDRO-IMIDAZOPYRIDINONES | DOMINIQUE ROMYR | 2008-10-16 | — | — | US | disclosed |