SCHEMBL19865078

SCHEMBL19865078

CO[Si](CCN1CCC(C)CC1)(OC)O[Si](CCN1CCN(C)CC1)(OC)OC

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 1/20 0.40
PRMT6 Q96LA8 1/20 0.40
PRMT1 Q99873 1/20 0.40
PRMT8 Q9NR22 1/20 0.40
ACHE P22303 2/20 0.35
HRH3 Q9Y5N1 2/20 0.35
SIGMAR1 Q99720 7/20 0.35
POLB P06746 1/20 0.34
HTT P42858 1/20 0.34
ALDH1A1 P00352 1/20 0.34
KMT2A Q03164 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
KDM4E B2RXH2 1/20 0.33
RECQL P46063 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20463568 0.88 CSNK2A2 (0.36) SIGMAR1ALDH1A1KDM4E
SCHEMBL22397861 0.78 CSNK2A2 (0.41) HRH3SIGMAR1ALDH1A1KMT2A
SCHEMBL19853579 0.76 CARM1 (0.56) CARM1PRMT6PRMT1PRMT8ACHE
SCHEMBL9517605 0.76 CARM1 (0.44) CARM1PRMT6PRMT1PRMT8HRH3
SCHEMBL18772772 0.70 CARM1 (0.48) CARM1PRMT6PRMT1PRMT8ACHE
SCHEMBL302762 0.70 CSNK2A2 (0.43) HRH3SIGMAR1ALDH1A1
SCHEMBL4062722 0.68 SIGMAR1 (0.32) SIGMAR1
SCHEMBL27327213 0.67 CARM1 (0.45) CARM1PRMT6PRMT1PRMT8ACHE
SCHEMBL20234635 0.67 CARM1 (0.65) CARM1PRMT6PRMT1PRMT8ACHE
SCHEMBL20730385 0.67 PAOX (0.46) HRH3SIGMAR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3281958-A1 MODIFYING AGENT, AND MODIFIED CONJUGATED DIENE-BASED POLYMER PRODUCED USING SAME LG Chem, Ltd. (KR) 2018-02-14 EP disclosed