Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VEGFA | P15692 | 12/20 | 0.54 |
| ▸ | EPAS1 | Q99814 | 12/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19865176 | 0.84 | EPAS1 (0.59) | VEGFAEPAS1 | |
| SCHEMBL19865424 | 0.83 | VEGFA (0.52) | VEGFAEPAS1 | |
| SCHEMBL19865425 | 0.82 | EPAS1 (0.65) | VEGFAEPAS1CYP2C9 | |
| SCHEMBL19865265 | 0.80 | EPAS1 (0.60) | VEGFAEPAS1 | |
| SCHEMBL19865225 | 0.76 | VEGFA (0.54) | VEGFAEPAS1CYP3A4CYP2C9 | |
| SCHEMBL19865223 | 0.76 | VEGFA (0.54) | VEGFAEPAS1CYP3A4CYP2C9 | |
| SCHEMBL19865336 | 0.76 | VEGFA (0.43) | VEGFAEPAS1 | |
| SCHEMBL21857881 | 0.72 | VEGFA (0.67) | VEGFAEPAS1CYP3A4CYP2C9 | |
| SCHEMBL19865466 | 0.72 | EPAS1 (0.52) | VEGFAEPAS1 | |
| SCHEMBL21857957 | 0.71 | VEGFA (0.64) | VEGFAEPAS1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018031680-A1 | NOVEL COMPOUNDS, USES AND METHODS FOR THEIR PREPARATION | FRONTHERA U.S. PHARMACEUTICALS LLC (US) | 2018-02-15 | — | — | WO | disclosed |