SCHEMBL1986557

SCHEMBL1986557

CC(=S)N1CCOCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14451158 0.97 SMN1; SMN2 (0.58)
SCHEMBL14451159 0.97 SMN1; SMN2 (0.58)
Pyridine SCHEMBL27502406 0.82 ALDH1A1 (0.45)
SCHEMBL1681337 0.78
SCHEMBL1266163 0.77
SCHEMBL3364313 0.74
SCHEMBL10921979 0.74
SCHEMBL22121714 0.74
SCHEMBL10026536 0.74 CA12 (0.59)
SCHEMBL7331881 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114907289-A Anti-tumor compound and application thereof in preparing anti-tumor medicine 梁姚(苏州)生物科技有限公司 2022-08-16 CN disclosed
US-20160199297-A1 BIODEGRADABLE INTRAVITREAL TYROSINE KINASE IMPLANTS ALLERGAN, INC. 2016-07-14 US disclosed
US-9334238-B2 N-substituted pyridinylidenes for combating animal pests BASF SE (DE) 2016-05-10 US disclosed
WO-2016034703-A1 FUSED HETEROCYCLIC OR CARBOCYCLIC COMPOUNDS CARRYING A SUBSTITUTED CYCLOALIPHATIC RADICAL AND USE THEREOF FOR TREATING VASOPRESSIN-RELATED DISEASES AbbVie Deutschland GmbH & Co. KG (DE) 2016-03-10 WO disclosed
US-9273086-B2 Protected monomer and method of final deprotection for RNA synthesis AGILENT TECHNOLOGIES, INC. (US) 2016-03-01 US disclosed
US-9233070-B2 Biodegradable intravitreal tyrosine kinase implants ALLERGAN, INC. (US) 2016-01-12 US disclosed
US-20160002282-A1 Protected Monomer and Method of Final Deprotection for RNA Synthesis AGILENT TECHNOLOGIES, INC. 2016-01-07 US disclosed
CN-105001271-A Neodymium/sodium mixed bimetallic complex and preparation method and application thereof UNIV ANHUI 2015-10-28 CN disclosed
US-9056045-B2 Intraocular biodegradable microspheres ALLERGAN, INC. (US) 2015-06-16 US disclosed
US-20150065501-A1 N-substituted hetero-bicyclic furanone derivatives for combating animal BASF SE (DE) 2015-03-05 US disclosed
US-20080260803-A1 Producing eye insertable drug delivery agent; extruding active ingredient with polyvinyl alcohol free biodegradable polymer ALLERGAN,INC. (US) 2008-10-23 US disclosed
US-7414054-B2 3-(arylamino)methylene-1, 3-dihydro-2H-indol-2-ones as kinase inhibitors ALLERGAN, INC. (US) 2008-08-19 US disclosed
WO-2008089892-A1 PHENOTHIAZIN DERIVATES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS PHARMACEUTICALS SANOFI-AVENTIS (FR) 2008-07-31 WO disclosed
EP-1032568-B1 PROCESS FOR THE PREPARATION OF ISOFLAVONES UNIV MICHIGAN STATE (US) 2005-01-26 EP disclosed
EP-1032568-A4 PROCESS FOR THE PREPARATION OF ISOFLAVONES UNIV MICHIGAN STATE (US) 2003-03-05 EP disclosed
EP-1032568-A1 PROCESS FOR THE PREPARATION OF ISOFLAVONES MICHIGAN STATE UNIVERSITY (US) 2000-09-06 EP disclosed
WO-2000015627-A1 PROCESS FOR THE PREPARATION OF ISOFLAVONES MICHIGAN STATE UNIVERSITY (US) 2000-03-23 WO disclosed
US-5981775-A FROM A 2'-HYDROXYDEOXYBENZOIN USING PREPARED N,N'-DIMETHYL(CHLOROMETHYLENE)AMMONIUM CHLORIDE AS A REACTANT IN BORONTRIFLUORIDE ETHERATE OR OTHER LEWIS ACID AS A SOLVENT BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) 1999-11-09 US disclosed
CN-1166169-A Heterocyclic compounds, useful as allosteric effectors at muscarinic receptors SANKYO CO (JP) 1997-11-26 CN disclosed
US-4149413-A THERMOCHROMIC THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHER IRELAND (GB) 1979-04-17 US disclosed