Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.47 |
| ▸ | MAPT | P10636 | 9/20 | 0.47 |
| ▸ | POLB | P06746 | 7/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | LDHA | P00338 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.45 |
| ▸ | G6PD | P11413 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6721129 | 0.75 | MAPT (0.65) | KDM4EMAPTPOLBL3MBTL1GAA | |
| SCHEMBL22903822 | 0.74 | KDM4E (0.57) | KDM4EMAPTPOLBL3MBTL1GAA | |
| SCHEMBL13548901 | 0.74 | MAPT (0.68) | KDM4EMAPTPOLBL3MBTL1GAA | |
| SCHEMBL17793849 | 0.71 | MAPT (0.38) | KDM4EMAPTPOLBL3MBTL1GAA | |
| SCHEMBL6721172 | 0.69 | MAPT (0.78) | KDM4EMAPTPOLBL3MBTL1GAA | |
| SCHEMBL19420133 | 0.65 | MAPT (0.76) | KDM4EMAPTPOLBL3MBTL1LDHA | |
| SCHEMBL6721119 | 0.65 | KDM4E (0.69) | KDM4EMAPTPOLBL3MBTL1GAA | |
| SCHEMBL19519001 | 0.64 | KDM1A (0.43) | KDM4EMAPTPOLBGAAALDH1A1 | |
| SCHEMBL6721166 | 0.64 | MAPT (1.00) | KDM4EMAPTPOLBL3MBTL1GAA | |
| SCHEMBL6721168 | 0.64 | MAPT (0.68) | KDM4EMAPTPOLBL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180042935-A1 | THERAMUTEIN MODULATORS | HMI Medical Innovations, LLC | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180042935-A1 | THERAMUTEIN MODULATORS | TSG101, SERPINE1, PLAUR | KDM4E 4221/4885MAPT 2984/4885POLB 2649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.