Sugi Predict

Sugi Predict / Targets / TSG101

TSG101

Tumor susceptibility gene 101 protein · Q99816 · TSG101 on Sugi Atlas →

90 patent compounds predicted against TSG101, 19 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL29321848 SCHEMBL29321848 0.40 19/20
SCHEMBL29321871 SCHEMBL29321871 0.35 19/20
SCHEMBL15828661 SCHEMBL15828661 0.55 17/20
SCHEMBL19365089 SCHEMBL19365089 0.56 16/20
SCHEMBL12122107 SCHEMBL12122107 0.54 16/20
SCHEMBL22958041 SCHEMBL22958041 0.53 16/20
SCHEMBL10167164 SCHEMBL10167164 0.48 11/20
SCHEMBL10182947 SCHEMBL10182947 0.48 11/20
SCHEMBL15591315 SCHEMBL15591315 0.48 11/20
SCHEMBL15099968 SCHEMBL15099968 0.47 11/20
SCHEMBL25888233 SCHEMBL25888233 0.42 6/20
SCHEMBL14271924 SCHEMBL14271924 0.47 5/20
SCHEMBL13754061 SCHEMBL13754061 0.48 3/20
SCHEMBL22328142 SCHEMBL22328142 0.37 3/20
SCHEMBL22328123 SCHEMBL22328123 0.37 3/20
SCHEMBL22328133 SCHEMBL22328133 0.36 3/20
SCHEMBL22730942 SCHEMBL22730942 0.36 3/20
SCHEMBL22328139 SCHEMBL22328139 0.36 3/20
SCHEMBL22328141 SCHEMBL22328141 0.34 3/20

Clinical trials — most relevant to TSG101 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA nanRECRUITING
Evaluation of Serum Gasdermin D Level As a Potential Biomarker of Disease Activity in Vitiligo Patients nanUNKNOWN
Study of Blood and Tissue Samples From Patients With Stomach Cancer, Esophageal Cancer, or Gastroesophageal Junction Cancer nanUNKNOWN
Characterization of Diseases With Salivary Gland Involvement nanRECRUITING
Identification of Prostate Cancer Genes nanCOMPLETED
Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated Conditions nanRECRUITING
Genetic Basis of Abdominal Aortic Aneurysm nanCOMPLETED
Gene Analysis in Studying Susceptibility to Wilms Tumor nanCOMPLETED
Study of Blood Samples From Patients With Ewing Sarcoma and Their Relatives nanCOMPLETED
Inflammatory Genomics in Human Carotid Artery Disease nanCOMPLETED
Evaluating Cascade Communication Methods nanCOMPLETED
Inherited Cancer Early Diagnosis (ICED) Study nanUNKNOWN
The Andromeda Study.Predictive Value of Combined Criteria to Tailor Breast Cancer Screening. nanCOMPLETED
Risk Burden of Lipoprotein Metabolic Gene Haplotypes nanCOMPLETED
Immunogenetic Modulators of Mucosal Protection From HIV-1 nanCOMPLETED
Cascade Testing in Families With Newly Diagnosed Hereditary Breast and Ovarian Cancer Syndrome nanACTIVE_NOT_RECRUITING
Esophageal Cancer Genetics Studies nanCOMPLETED
Modifying Genes in Neurofibromatosis 1 nanUNKNOWN
Genes Involved in Resistance or Susceptibility to Hepatitis B Virus nanCOMPLETED
Family Study of Melanoma in Italy nanCOMPLETED
Celiac Disease Genomic Environmental Microbiome and Metabolomic Study nanRECRUITING
Biomarker Monitoring in TP53 Mutation Carriers nanCOMPLETED
Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of Cancer nanACTIVE_NOT_RECRUITING
Patient-derived Glioma Stem Cell Organoids nanACTIVE_NOT_RECRUITING
Quantitative Assessment of the Etiologies of Megalencephaly Associated With a Detectable Tumor Risk nanNOT_YET_RECRUITING
Identification of New Colorectal Cancer Genes nanCOMPLETED
Incidental Genomics nanACTIVE_NOT_RECRUITING
Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq) nanRECRUITING
Development of Polygenic Risk Scores in Colon Cancer Patients Through the Study of Ancestry and Diversity in Genetic Maps of the Brazilian Population - ORIGEM Project nanENROLLING_BY_INVITATION
Screening for Early Pancreatic Neoplasia (Cancer of the Pancreas Screening or CAPS4 Study) nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a TSG101 binder may also engage these)

ProteinNameSimilarity
Q61187 — 0.962 Q61187 →
Q6IRE4 — 0.955 Q6IRE4 →
Q5XIT1 — 0.946 Q5XIT1 →
Q6PER3 — 0.945 Q6PER3 →
Q9UPY8 — 0.940 Q9UPY8 →
Q6AYU1 — 0.940 Q6AYU1 →
Q5F398 — 0.940 Q5F398 →
Q5NVP9 — 0.940 Q5NVP9 →
A1L167 — 0.939 A1L167 →
Q5R532 — 0.939 Q5R532 →
Q13888 — 0.938 Q13888 →
A0PJN4 — 0.937 A0PJN4 →
Q4R9A8 — 0.937 Q4R9A8 →
Q2TBV5 — 0.937 Q2TBV5 →
Q7SXR3 — 0.936 Q7SXR3 →
Q6GR10 — 0.936 Q6GR10 →
A1L3K1 — 0.936 A1L3K1 →
Q9JIB4 — 0.935 Q9JIB4 →
Q6P1K8 — 0.935 Q6P1K8 →
Q4VC33 — 0.935 Q4VC33 →
Q7L5Y9 — 0.935 Q7L5Y9 →
Q5TDH0 — 0.934 Q5TDH0 →
B5DFI8 — 0.933 B5DFI8 →
Q921J4 — 0.933 Q921J4 →
Q8R3T5 — 0.932 Q8R3T5 →
Q6PFJ9 — 0.932 Q6PFJ9 →
Q8C6G8 — 0.931 Q8C6G8 →
Q5RKJ1 — 0.931 Q5RKJ1 →
Q99LD4 — 0.931 Q99LD4 →
A0JN27 — 0.931 A0JN27 →