Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 6/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24124963 | 0.98 | CA2 (0.53) | HDAC8HDAC7HDAC6HDAC9HDAC5 | |
| SCHEMBL21141383 | 0.90 | HDAC7 (0.50) | HDAC8HDAC7HDAC6HDAC9HDAC5 | |
| SCHEMBL25732354 | 0.88 | CA2 (0.66) | CA2CA1MAPK1PDFTSHR | |
| SCHEMBL2058687 | 0.82 | CA2 (0.68) | CA2CA1MAPK1PDFTSHR | |
| SCHEMBL12790571 | 0.81 | HDAC8 (0.52) | HDAC8HDAC7HDAC6HDAC9HDAC5 | |
| SCHEMBL22304387 | 0.80 | CA2 (0.50) | HDAC8HDAC7HDAC6HDAC9HDAC5 | |
| SCHEMBL21340001 | 0.79 | HDAC8 (0.56) | HDAC8HDAC7HDAC6HDAC9HDAC5 | |
| SCHEMBL1388451 | 0.79 | CA2 (0.44) | CA2CA1MAPK1DPP4DPP8 | |
| SCHEMBL13715798 | 0.79 | PLA2G2C (0.59) | CA2CA1MAPK1PLA2G2C | |
| SCHEMBL1388452 | 0.79 | CA2 (0.48) | CA2CA1MAPK1DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3099675-B1 | INDAZOLE COMPOUNDS AS 5-HT4 RECEPTOR AGONISTS | SUVEN LIFE SCIENCES LTD (IN) | 2018-02-14 | — | — | EP | disclosed |