Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19859847 | 1.00 | HTR6 (0.35) | HTR6CHRNB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL21085843 | 1.00 | HTR6 (0.35) | HTR6CHRNB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL19859848 | 1.00 | HTR6 (0.35) | HTR6CHRNB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL19859849 | 1.00 | HTR6 (0.35) | HTR6CHRNB1CHRNB2CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL21046980 | 0.99 | HTR6 (0.36) | HTR6 | |
| Hydrochloric Acid SCHEMBL21046979 | 0.99 | HTR6 (0.36) | HTR6 | |
| Hydrochloric Acid SCHEMBL21046981 | 0.99 | HTR6 (0.36) | HTR6 | |
| SCHEMBL21047352 | 0.78 | KDM2B (0.40) | — | |
| SCHEMBL21047350 | 0.78 | KDM2B (0.40) | — | |
| SCHEMBL21047354 | 0.78 | KDM2B (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018031877-A1 | FUMAGILLOL COMPOUNDS AND METHODS OF MAKING AND USING SAME | ZAFGEN, INC. (US) | 2018-02-15 | — | — | WO | disclosed |