Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.49 |
| ▸ | FOLR1 | P15328 | 6/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 5/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19627547 | 0.88 | FOLH1 (0.50) | FOLH1FOLR1HTR1AMMP2MMP9 | |
| SCHEMBL25931741 | 0.88 | FOLH1 (0.57) | FOLH1FOLR1HTR1AMMP2MMP9 | |
| SCHEMBL18874921 | 0.87 | FOLH1 (0.50) | FOLH1FOLR1HTR1AMMP2MMP9 | |
| SCHEMBL10026006 | 0.87 | FOLH1 (0.49) | FOLH1FOLR1HTR1AMMP2MMP9 | |
| SCHEMBL26316502 | 0.86 | FOLH1 (0.52) | FOLH1FOLR1HTR1APRMT5CARM1 | |
| SCHEMBL14703625 | 0.86 | FOLH1 (0.56) | FOLH1FOLR1HTR1AHRH2HRH4 | |
| SCHEMBL14703623 | 0.86 | FOLH1 (0.52) | FOLH1FOLR1HTR1AHRH2HRH4 | |
| SCHEMBL17356823 | 0.85 | FOLH1 (0.53) | FOLH1FOLR1HTR1AHRH2HRH4 | |
| SCHEMBL14703613 | 0.85 | FOLR1 (0.55) | FOLH1FOLR1HTR1AMMP2MMP9 | |
| SCHEMBL17546355 | 0.85 | FOLR1 (0.52) | FOLH1FOLR1HTR1AMMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180045738-A1 | METHODS OF USE FOR INTERMEDIATE FILAMENT PROTEIN PROBES | UNIVERSITY OF CONNECTICUT | 2018-02-15 | — | — | US | disclosed |