Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19869925 | 1.00 | TRPV6 (0.45) | TRPV6TLR7KDM4ETDP1CHRNB2 | |
| SCHEMBL24556440 | 1.00 | TRPV6 (0.45) | TRPV6TLR7KDM4ETDP1CHRNB2 | |
| SCHEMBL19869915 | 1.00 | TRPV6 (0.45) | TRPV6TLR7KDM4ETDP1CHRNB2 | |
| SCHEMBL24556578 | 1.00 | TRPV6 (0.45) | TRPV6TLR7KDM4ETDP1CHRNB2 | |
| Hydrochloric Acid SCHEMBL19857627 | 0.99 | TRPV6 (0.44) | TRPV6TLR7KDM4ETDP1CHRNB2 | |
| Hydrochloric Acid SCHEMBL19857668 | 0.99 | TRPV6 (0.44) | TRPV6TLR7KDM4ETDP1CHRNB2 | |
| Hydrochloric Acid SCHEMBL19857665 | 0.99 | TRPV6 (0.44) | TRPV6TLR7KDM4ETDP1CHRNB2 | |
| SCHEMBL3032912 | 0.81 | TLR7 (0.44) | TLR7MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL31688136 | 0.81 | TLR7 (0.44) | TLR7MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL24556470 | 0.78 | TRPV6 (0.44) | TRPV6TLR7KDM4ETDP1PYCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11319318-B2 | Pyridinones and isoquinolinones as inhibitors of the bromodomain BRD9 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2022-05-03 | — | — | US | disclosed |
| US-20180044335-A1 | New Pyridinones and Isoquinolinones as Inhibitors of the Bromodomain BRD9 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2018-02-15 | — | — | US | disclosed |
| US-20180044335-A1 | New Pyridinones and Isoquinolinones as Inhibitors of the Bromodomain BRD9 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180044335-A1 | New Pyridinones and Isoquinolinones as Inhibitors of the Bromodomain BRD9 | BRD9, BRD1, BRD2 | TRPV6 3899/4885TLR7 2801/4885KDM4E 1154/4885 |
| US-11319318-B2 | Pyridinones and isoquinolinones as inhibitors of the bromodomain BRD9 | BRD9, BRD1, BRD2 | TRPV6 3797/4885TLR7 2591/4885KDM4E 1262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.