Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PTPRA | P18433 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.34 |
| ▸ | ITGAL | P20701 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19872755 | 0.87 | KDM4E (0.46) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL18000267 | 0.86 | PTPRA (0.55) | KDM4EPOLBMAPTRECQLL3MBTL1 | |
| SCHEMBL19872705 | 0.86 | KDM4E (0.45) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL18000164 | 0.86 | PTPRA (0.55) | KDM4EPOLBMAPTRECQLL3MBTL1 | |
| SCHEMBL18029200 | 0.86 | PTPRA (0.55) | KDM4EPOLBMAPTRECQLL3MBTL1 | |
| SCHEMBL21392083 | 0.83 | MAPT (0.43) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL18509424 | 0.79 | GPR17 (0.50) | CYP2C19NQO2MTNR1AMTNR1BHTR1A | |
| SCHEMBL18029335 | 0.74 | PTPRA (0.55) | KDM4EMAPTPTPRACYP2C19HTR1A | |
| SCHEMBL18000105 | 0.74 | PTPRA (0.55) | KDM4EMAPTPTPRACYP2C19HTR1A | |
| SCHEMBL18000103 | 0.74 | PTPRA (0.55) | KDM4EMAPTPTPRACYP2C19HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180044291-A1 | ARTIFICIAL SELF-SUFFICIENT CYTOCHROME P450S | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180044291-A1 | ARTIFICIAL SELF-SUFFICIENT CYTOCHROME P450S | CYP4F2, POR, CYP4F3 | KDM4E 3127/4885APAF1 1399/4885POLB 2407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.