Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PTPRA | P18433 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | FBP1 | P09467 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18000323 | 0.87 | PTPRA (0.52) | MAPTKDM4EPOLBRECQLL3MBTL1 | |
| SCHEMBL18000327 | 0.87 | PTPRA (0.52) | MAPTKDM4EPOLBRECQLL3MBTL1 | |
| SCHEMBL18029232 | 0.87 | PTPRA (0.52) | MAPTKDM4EPOLBRECQLL3MBTL1 | |
| SCHEMBL19872755 | 0.84 | KDM4E (0.46) | MAPTKDM4EPOLBAPAF1RECQL | |
| SCHEMBL20935014 | 0.83 | PTPRA (0.37) | MAPTPTPRACYP2C19NQO2MTNR1A | |
| SCHEMBL19872705 | 0.83 | KDM4E (0.45) | MAPTKDM4EPOLBAPAF1RECQL | |
| SCHEMBL19872691 | 0.83 | KDM4E (0.45) | MAPTKDM4EPOLBAPAF1RECQL | |
| SCHEMBL21392178 | 0.76 | KDM4E (0.45) | MAPTKDM4EPOLBAPAF1RECQL | |
| SCHEMBL18000103 | 0.71 | PTPRA (0.55) | MAPTKDM4EPTPRACYP2C19KMT2A | |
| SCHEMBL18029335 | 0.71 | PTPRA (0.55) | MAPTKDM4EPTPRACYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11078467-B2 | Highly active self-sufficient nitration biocatalysts | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2021-08-03 | — | — | US | disclosed |
| US-20190292527-A1 | HIGHLY ACTIVE SELF-SUFFICIENT NITRATION BIOCATALYSTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11078467-B2 | Highly active self-sufficient nitration biocatalysts | POR, CYP4F3, CBR3 | MAPT 3914/4885KDM4E 2974/4885POLB 4146/4885 |
| US-20190292527-A1 | HIGHLY ACTIVE SELF-SUFFICIENT NITRATION BIOCATALYSTS | POR, CYP4F3, CBR3 | MAPT 3914/4885KDM4E 2974/4885POLB 4146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.