Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | APAF1 | O14727 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NQO2 | P16083 | 2/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | PTPRA | P18433 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18509505 | 0.87 | PTPRA (0.55) | KDM4EMAPTNQO2MTNR1AMTNR1B | |
| SCHEMBL18000298 | 0.87 | PTPRA (0.55) | KDM4EMAPTNQO2MTNR1AMTNR1B | |
| SCHEMBL18000149 | 0.87 | PTPRA (0.55) | KDM4EMAPTNQO2MTNR1AMTNR1B | |
| SCHEMBL21392178 | 0.84 | KDM4E (0.45) | KDM4EPOLBAPAF1MAPTRECQL | |
| SCHEMBL18509502 | 0.80 | NQO2 (0.51) | KDM4EPOLBMAPTRECQLL3MBTL1 | |
| SCHEMBL19872755 | 0.76 | KDM4E (0.46) | KDM4EPOLBAPAF1MAPTRECQL | |
| SCHEMBL25001166 | 0.75 | MTNR1A (0.76) | KDM4EMAPTNQO2MTNR1AMTNR1B | |
| SCHEMBL30580919 | 0.75 | MTNR1A (0.76) | KDM4EMAPTNQO2MTNR1AMTNR1B | |
| SCHEMBL14032218 | 0.74 | PTPRA (0.60) | KDM4EPOLBAPAF1MAPTRECQL | |
| SCHEMBL18000202 | 0.73 | PTPRA (0.59) | KDM4EPOLBMAPTRECQLL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180044291-A1 | ARTIFICIAL SELF-SUFFICIENT CYTOCHROME P450S | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180044291-A1 | ARTIFICIAL SELF-SUFFICIENT CYTOCHROME P450S | CYP4F2, POR, CYP4F3 | KDM4E 3127/4885POLB 2407/4885APAF1 1399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.