Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | F7 | P08709 | 2/20 | 0.46 |
| ▸ | F3 | P13726 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2518545 | 1.00 | ALDH1A1 (0.54) | ALDH1A1CYP3A4ALOX15HSD17B10TDP1 | |
| SCHEMBL2518096 | 0.96 | ALDH1A1 (0.52) | ALDH1A1CYP3A4ALOX15HSD17B10TDP1 | |
| SCHEMBL19873143 | 0.93 | ALB (0.49) | ALDH1A1CYP3A4ALOX15HSD17B10TDP1 | |
| SCHEMBL29761138 | 0.93 | ALB (0.49) | ALDH1A1CYP3A4ALOX15HSD17B10TDP1 | |
| SCHEMBL2518734 | 0.93 | ALB (0.49) | ALDH1A1CYP3A4ALOX15HSD17B10TDP1 | |
| SCHEMBL19873149 | 0.92 | ALB (0.47) | ALDH1A1CYP3A4ALOX15HSD17B10TDP1 | |
| SCHEMBL2517222 | 0.92 | ALDH1A1 (0.55) | ALDH1A1CYP3A4ALOX15HSD17B10TDP1 | |
| SCHEMBL2519158 | 0.91 | ALDH1A1 (0.52) | ALDH1A1CYP3A4ALOX15HSD17B10TDP1 | |
| SCHEMBL19873141 | 0.91 | ALB (0.51) | ALBPTGS2KMT2AKDM4ELMNA | |
| SCHEMBL4098119 | 0.91 | ALB (0.51) | ALBPTGS2KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753708-B1 | NOVEL SIRTUIN ACTIVATING COMPOUNDS AND METHODS FOR MAKING THE SAME | UNIV BRIGHAM YOUNG (US) | 2018-02-21 | — | — | EP | claimed |