Toluene

Toluene

SCHEMBL19873397

Cc1ccccc1.OCC12CC3CC(CC(C3)C1)C2

nearest known ligand 0.46

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 9/20 0.46
ESR1 P03372 1/20 0.45
CYP2C9 P11712 1/20 0.45
ESR2 Q92731 1/20 0.45
EPHX2 P34913 4/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
OPRK1 P41145 1/20 0.42
LMNA P02545 2/20 0.41
TSHR P16473 1/20 0.41
ALOX12 P18054 1/20 0.41
ACHE P22303 1/20 0.41
ALDH1A1 P00352 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25797414 0.77 GRIN2D (0.52) ESR1CYP2C9ESR2EPHX2MEN1
SCHEMBL25797411 0.77 GRIN2D (0.52) ESR1CYP2C9ESR2EPHX2MEN1
SCHEMBL236361 0.77 GRIN2D (0.52) ESR1CYP2C9ESR2EPHX2MEN1
Fluoride SCHEMBL1394508 0.75 GRIN2D (0.50) ESR1CYP2C9ESR2EPHX2KMT2A
Adamantane SCHEMBL28179110 0.75 ACHE (0.65) CYP2C9LMNATSHRALOX12ACHE
SCHEMBL354182 0.68 MEN1 (0.56) P2RX7EPHX2MEN1KMT2AOPRK1
Toluene SCHEMBL5199381 0.67 ACHE (0.69) MEN1KMT2ALMNATSHRALOX12
Toluene SCHEMBL5198578 0.67 ACHE (0.69) MEN1KMT2ALMNATSHRALOX12
Toluene SCHEMBL22729215 0.67 ACHE (0.69) MEN1KMT2ALMNATSHRALOX12
Toluene SCHEMBL28769535 0.67 ACHE (0.69) MEN1KMT2ALMNATSHRALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3284760-A1 POLYMER, MOLDING MATERIAL AND RESIN MOLDED BODY Zeon Corporation (JP) 2018-02-21 EP disclosed