Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 2/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 2/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | NEK2 | P51955 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19873503 | 0.77 | CHRNA7 (0.46) | CAMK2DTERTACP1GBA1RAD52 | |
| SCHEMBL16928500 | 0.77 | MAP3K5 (0.54) | CSNK2A1NEK2BRAF | |
| SCHEMBL19873505 | 0.76 | CAMK2D (0.42) | CAMK2DTERTACP1RAD52BRAF | |
| SCHEMBL19873454 | 0.76 | CAMK2D (0.44) | CAMK2DACP1GBA1BRAF | |
| SCHEMBL19873488 | 0.75 | GBA1 (0.50) | ACP1GBA1 | |
| SCHEMBL16928527 | 0.74 | ACP1 (0.56) | CAMK2DACP1 | |
| SCHEMBL19873479 | 0.74 | ACP1 (0.45) | CAMK2DACP1RAD52 | |
| SCHEMBL16928011 | 0.74 | ACP1 (0.48) | CAMK2DACP1RAD52 | |
| SCHEMBL19873522 | 0.74 | CHRNB4 (0.47) | CAMK2DACP1GBA1 | |
| SCHEMBL16928205 | 0.73 | NMT1 (0.51) | ACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970153-B1 | TRIAZINE COMPOUNDS AND COMPOSITIONS THEREOF AND METHODS FOR TREATING MALARIA AND CHEMOPROPHYLAXIS | THE US SECRETARY OF THE ARMY ON BEHALF OF WALTER REED ARMY INSTITUTE OF RESEARCH (US) | 2018-02-21 | — | — | EP | disclosed |