SCHEMBL19874474

SCHEMBL19874474

O=S(=O)(Cl)c1ccc(OCCCCCCCCCCOc2ccc(S(=O)(=O)Cl)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA12 O43570 8/20 0.52
CA1 P00915 8/20 0.52
CA2 P00918 8/20 0.52
CA9 Q16790 8/20 0.52
CA7 P43166 2/20 0.52
TSHR P16473 2/20 0.52
CA4 P22748 4/20 0.51
GAA P10253 1/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
HRH3 Q9Y5N1 2/20 0.45
KCNH2 Q12809 1/20 0.44
ALDH1A1 P00352 2/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
KCNA3 P22001 1/20 0.43
MAPK1 P28482 1/20 0.42
RECQL P46063 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19874580 1.00 CA12 (0.52) CA12CA1CA2CA9CA7
SCHEMBL13600617 0.92 CA12 (0.49) CA12CA1CA2CA9CA7
SCHEMBL10600260 0.91 TSHR (0.62) CA12CA1CA2CA9CA7
SCHEMBL10608025 0.91 TSHR (0.62) CA12CA1CA2CA9CA7
SCHEMBL7766693 0.91 TSHR (0.62) CA12CA1CA2CA9CA7
SCHEMBL10708683 0.91 TSHR (0.62) CA12CA1CA2CA9CA7
SCHEMBL10610971 0.91 TSHR (0.62) CA12CA1CA2CA9CA7
SCHEMBL10606406 0.91 TSHR (0.62) CA12CA1CA2CA9CA7
SCHEMBL3369946 0.91 TSHR (0.62) CA12CA1CA2CA9CA7
SCHEMBL10606881 0.91 TSHR (0.62) CA12CA1CA2CA9CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3268352-B1 NON EXPLOSIVE BIS-SULFONYL AZIDES DYNAMIT NOBEL GMBH EXPLOSIVSTOFF UND SYSTEMTECHNIK (DE) 2020-06-10 EP disclosed
US-10385016-B2 Non explosive bis-sulfonyl azides DYNAMIT NOBEL GMBH EXPLOSIVSTOFF-UND SYSTEMTECHNIK (DE) 2019-08-20 US disclosed
US-20180050988-A1 NON EXPLOSIVE BIS-SULFONYL AZIDES DYNAMIT NOBEL GMBH EXPLOSIVSTOFF- UND SYSTEMTECHNIK (DE) 2018-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10385016-B2 Non explosive bis-sulfonyl azides ARSA, MSRB3, NES CA12 3555/4885CA1 2823/4885CA2 1475/4885
US-20180050988-A1 NON EXPLOSIVE BIS-SULFONYL AZIDES ARSA, MSRB3, NES CA12 3519/4885CA1 2828/4885CA2 1444/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.