MSRB3 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to MSRB3 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
A Phase IV Study of Rebif ® 44mcg Administered Three Times Per Week by Subcutaneous Injection Compared With no Treatment in the Therapy of Relapsing Multiple Sclerosis After Mitoxantrone	PHASE4	COMPLETED
Study of SGN1 in Patients With Advanced Solid Tumor	PHASE1/PHASE2	RECRUITING
Homocystinuria: Treatment With N-Acetylcysteine	PHASE2	COMPLETED
Study of SGN1 Administered Via Intratumoral Injection in Patients With Advanced Solid Tumor	PHASE1/PHASE2	RECRUITING
Dietary Effects of Sulfur Amino Acids	nan	COMPLETED
Plant-based Diets and Body Weight and Selected Metabolic Parameters Management in Obese Patients.	nan	COMPLETED
Effect of Sulfur Amino Acid Depletion and Acetaminophen on Plasma Glutatione	nan	COMPLETED
Genomics and Epigenomics for New Insights in fEmale OAB (GENIE) Study	nan	COMPLETED
Early Nutritional Intervention in Patients With Autism Spectrum Disorders	nan	COMPLETED
Molecular Epidemiology of Parkinson's Disease	nan	COMPLETED
Homocysteine and Coronary Artery Disease	nan	COMPLETED
Polymorphisms of Interleukins, Glypican, and Human Leukocyte Antigen Genes and Treatment Response in Multiple Sclerosis.	nan	UNKNOWN
Genetic Association of Diabetic Retinopathy-1	nan	UNKNOWN
Thiol/Disulphide Homeostasis in Unexplained Infertility	nan	COMPLETED
Genetic Variants and Regulation of Specialized Pro-resolving Mediator	nan	RECRUITING
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases	nan	UNKNOWN
External Nitric Oxide Measurement Through SNO Degradation	nan	ENROLLING_BY_INVITATION
Adenosylmethionine Metabolism in Human Inflammation	nan	UNKNOWN
Molecular Genetic Epidemiology of Endocardial Cushion Defects - SCOR in Pediatric Cardiovascular Disease	nan	COMPLETED
Melanocortin Gene Expression in Lymphocytes of Polymyalgia Patients	nan	COMPLETED
The Effect of Cigarette Smoke on Sleep Quality and Physical Activity in People With Multiple Sclerosis	nan	COMPLETED
Role and Interactions of Adenosine, Receptors, Methionine Cycle Nutritional, Metabolic and Genetic Determinants in the Onset of Atrial Fibrillation in Normal Heart	nan	UNKNOWN
Genetic Epidemiology of Sarcoidosis	nan	COMPLETED
Role of a Dietary Supplement in Lowering SAH in Healthy Adults With Elevated Plasma SAH and Normal Homocysteine Levels	nan	COMPLETED
Genetic Mechanisms of Chronic Obstructive Pulmonary Disease (COPD)	nan	COMPLETED
Ccf mtDNA as a Neurodegenerative Biomarker	nan	UNKNOWN
Genetic Variants Associated With Adolescent Suicide Attempts	nan	COMPLETED
Modeling DNA Diversity in Reverse Cholesterol Transport	nan	COMPLETED
Dietary Interventions During Living Kidney Donations	nan	RECRUITING
Choline Supplementation on Fetal Growth in Gestational Diabetes Mellitus	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a MSRB3 binder may also engage these)

Protein	Name	Similarity
Q5R930	—	1.000	Q5R930 →
Q0DC89	—	0.986	Q0DC89 →
Q8BU85	—	0.985	Q8BU85 →
Q78J03	—	0.984	Q78J03 →
Q9M0Z6	—	0.984	Q9M0Z6 →
Q8INK9	—	0.984	Q8INK9 →
Q9C8M2	—	0.983	Q9C8M2 →
O49707	—	0.982	O49707 →
Q8VY86	—	0.981	Q8VY86 →
Q6NW52	—	0.981	Q6NW52 →
Q9A6B1	—	0.981	Q9A6B1 →
Q9C5C8	—	0.980	Q9C5C8 →
A0K833	—	0.979	A0K833 →
B2VJ36	—	0.979	B2VJ36 →
Q89EM9	—	0.979	Q89EM9 →
B4RUW0	—	0.979	B4RUW0 →
Q8PWF5	—	0.979	Q8PWF5 →
Q1CJ76	—	0.978	Q1CJ76 →
B1JLG2	—	0.978	B1JLG2 →
Q4FZX5	—	0.978	Q4FZX5 →
Q10L32	—	0.978	Q10L32 →
B8GY23	—	0.978	B8GY23 →
B1YRN6	—	0.978	B1YRN6 →
Q2SJP9	—	0.977	Q2SJP9 →
A9AJS6	—	0.977	A9AJS6 →
B2K3R4	—	0.977	B2K3R4 →
B1JTT6	—	0.977	B1JTT6 →
Q8ZEK7	—	0.977	Q8ZEK7 →
Q6AUK5	—	0.977	Q6AUK5 →
A4TJB4	—	0.977	A4TJB4 →