⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL288323 | 0.75 | — | — | |
| SCHEMBL196011 | 0.71 | — | — | |
| SCHEMBL1416084 | 0.69 | — | — | |
| Propionaldehyde SCHEMBL7524407 | 0.69 | — | — | |
| SCHEMBL1632013 | 0.69 | — | — | |
| SCHEMBL129947 | 0.69 | — | — | |
| SCHEMBL19276 | 0.69 | — | — | |
| SCHEMBL21839372 | 0.69 | — | — | |
| SCHEMBL14763431 | 0.69 | — | — | |
| SCHEMBL285449 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 769 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024003259-A1 | TEAD INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2024-01-04 | — | — | WO | claimed |
| WO-2023225661-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-11-23 | — | — | WO | claimed |
| WO-2023064152-A1 | TRICYCLIC SULFAMIDES AND SULTAMS | MERCK SHARP & DOHME LLC (US) | 2023-04-20 | — | — | WO | claimed |
| CN-112313207-B | Cyano-substituted pyridine and cyano-substituted pyrimidine compounds, and preparation methods and applications thereof | 北京赛特明强医药科技有限公司 | 2023-02-14 | — | — | CN | claimed |
| CN-115666514-A | Injectable pharmaceutical composition and use thereof | 英特维特国际股份有限公司 | 2023-01-31 | — | — | CN | claimed |
| CN-115557907-A | 2,4, 5-trisubstituted 1,2, 4-triazolones as DHODH inhibitors | 拜耳股份有限公司 | 2023-01-03 | — | — | CN | claimed |
| CN-110023302-B | 2,4, 5-trisubstituted 1,2, 4-triazolones as DHODH inhibitors | 拜耳股份有限公司 | 2022-07-26 | — | — | CN | claimed |
| CN-112313207-A | Cyano-substituted pyridine and cyano-substituted pyrimidine compounds, and preparation methods and applications thereof | 北京赛特明强医药科技有限公司 | 2021-02-02 | — | — | CN | claimed |
| CN-112218860-A | Substituted phenylthiouracils, their salts and their use as herbicides | 先正达农作物保护股份公司 | 2021-01-12 | — | — | CN | claimed |
| CN-112154147-A | Substituted phenylthiouracils, their salts and their use as herbicides | 先正达农作物保护股份公司 | 2020-12-29 | — | — | CN | claimed |
| WO-2011048208-A1 | CAUSAL THERAPY OF DISEASES OR CONDITIONS ASSOCIATED WITH CNS OR PNS DEMYELINATION | UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN (IE) | 2011-04-28 | — | — | WO | claimed |
| CN-101778566-A | Isoxazoline compositions and their use as antiparasitics | INTERVET INT BV | 2010-07-14 | — | — | CN | claimed |
| US-20090018148-A1 | Xanthine Derivatives, Processes For Preparing Them And Their Uses | UCB PHARMA, S.A. (BE) | 2009-01-15 | — | — | US | claimed |
| US-20050197338-A1 | Substituted pyrazole urea compounds for the treatment of inflammation | PHARMACIA AND UPJOHN COMPANY LLC | 2005-09-08 | — | — | US | claimed |
| CN-1208319-C | 2-oxo-1-pyrrolidine derivatives, preparation method and use thereof | UCB SA (BE) | 2005-06-29 | — | — | CN | claimed |
| WO-2005037797-A1 | SUBSTITUTED PYRAZOLE UREA COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-04-28 | — | — | WO | claimed |
| EP-0791594-A2 | 2-Aryl-5,11-dihydro-6H-dipyrido 3,2-b:2',3'-e 1,4 diazepines and their use for the preparation of pharmaceutical compositions for the treatment of HIV infection | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1997-08-27 | — | — | EP | claimed |
| EP-0195731-B1 | SWEETENERS, PROCESS FOR SWEETENING VARIOUS PRODUCTS AND COMPOSITIONS CONTAINING SUCH SWEETENERS | NOFRE, Claude (FR) | 1990-01-24 | — | — | EP | claimed |
| EP-0321368-A1 | Heterocyclic N-carbamoyl, N-thiocarbamoyl or N-amidino-aminomalonyl or -aminosuccinyl amide derivatives as sweetening agents | NOFRE, Claude (FR) | 1989-06-21 | — | — | EP | claimed |
| EP-0195731-A2 | Sweeteners, process for sweetening various products and compositions containing such sweeteners | NOFRE, Claude (FR) | 1986-09-24 | — | — | EP | claimed |