Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoxaline SCHEMBL28773182 | 1.00 | ALDH1A1 (0.50) | ALDH1A1NCF1MAPTKDM4EPOLB | |
| Quinoxaline SCHEMBL28320470 | 0.94 | ALDH1A1 (0.46) | ALDH1A1NCF1MAPTKDM4EPOLB | |
| Quinoxaline SCHEMBL27910166 | 0.90 | ALDH1A1 (0.52) | ALDH1A1NCF1MAPTKDM4EPOLB | |
| Quinoxaline SCHEMBL5315 | 0.90 | ALDH1A1 (0.58) | ALDH1A1NCF1MAPTKDM4EPOLB | |
| Quinoxaline SCHEMBL6928518 | 0.90 | ALDH1A1 (0.58) | ALDH1A1NCF1MAPTKDM4EPOLB | |
| Quinoxaline SCHEMBL30320908 | 0.90 | ALDH1A1 (0.58) | ALDH1A1NCF1MAPTKDM4EPOLB | |
| Quinoxaline SCHEMBL29355228 | 0.90 | ALDH1A1 (0.58) | ALDH1A1NCF1MAPTKDM4EPOLB | |
| Quinoxaline SCHEMBL5358841 | 0.87 | ALDH1A1 (0.55) | ALDH1A1NCF1MAPTKDM4EPOLB | |
| Quinoxaline SCHEMBL2431603 | 0.87 | ALDH1A1 (0.55) | ALDH1A1NCF1MAPTKDM4EPOLB | |
| Quinoxaline SCHEMBL19877228 | 0.87 | ALDH1A1 (0.55) | ALDH1A1NCF1MAPTKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114409657-B | 4-aryl (methyl) imidazoline quinoxalinone compound and preparation method and application thereof | 湖南科技大学 | 2023-02-24 | — | — | CN | claimed |
| CN-112480016-B | (E) -1-acyl-1- (3-quinoxalinone) methyl ketoxime and synthesis method thereof | 杭州师范大学 | 2022-05-20 | — | — | CN | claimed |
| CN-114409657-A | 4-aryl (methyl) imidazoline quinoxalinone compound and preparation method and application thereof | 湖南科技大学 | 2022-04-29 | — | — | CN | claimed |
| CN-112480016-A | (E) -1-acyl-1- (3-quinoxalinone) methyl ketoxime and synthesis method thereof | 杭州师范大学 | 2021-03-12 | — | — | CN | claimed |
| CN-110437164-A | A kind of synthetic method of the position the C-3 alkyl substituted quinoxaline ketone derivatives based on Minisci reaction | UNIV ZHEJIANG TECHNOLOGY | 2019-11-12 | — | — | CN | claimed |
| CN-110105293-A | A kind of synthetic method of C-3 difluoromethyl substituted quinoxaline ketones derivant | 浙江工业大学 | 2019-08-09 | — | — | CN | claimed |
| CN-102124319-A | Method for evaluating high temperature wear life | DU PONT | 2011-07-13 | — | — | CN | claimed |
| CN-100558728-C | Calcitonin gene related peptide receptor antagonists | BRISTOL MYERS SQUIBB CO (US) | 2009-11-11 | — | — | CN | claimed |
| CN-1972929-A | Heterocyclic CGRP antagonists for the treatment of migraine | BRISTOL MYERS SQUIBB CO (US) | 2007-05-30 | — | — | CN | claimed |
| CN-1671711-A | Calcitonin gene related peptide receptor antagonists | BRISTOL MYERS SQUIBB CO (US) | 2005-09-21 | — | — | CN | claimed |
| CN-119390699-A | Synthesis method of pyrrolo [1,2-a ] quinoxaline-4 (5H) -ketone compound | 重庆文理学院 | 2025-02-07 | — | — | CN | disclosed |
| CN-119390699-A | Synthesis method of pyrrolo [1,2-a ] quinoxaline-4 (5H) -ketone compound | 重庆文理学院 | 2025-02-07 | — | — | CN | disclosed |
| CN-119118932-A | Preparation method of C3-alkyl substituted quinoxalinone compound under heterogeneous photocatalysis | 南京工业大学 | 2024-12-13 | — | — | CN | disclosed |
| CN-117756849-A | Preparation method of alkyl thiophosphate compounds containing quinoxalinone structural units | 湖南科技学院 | 2024-03-26 | — | — | CN | disclosed |
| CN-114230528-B | Method for preparing quinoxalinone derivative | 桂林理工大学 | 2024-02-06 | — | — | CN | disclosed |
| CN-1917921-A | Calcitonin gene related peptide receptor antagonists | BRISTOL MYERS SQUIBB CO (US) | 2007-02-21 | — | — | CN | disclosed |
| CN-1671711-A | Calcitonin gene related peptide receptor antagonists | BRISTOL MYERS SQUIBB CO (US) | 2005-09-21 | — | — | CN | disclosed |
| CN-1240211-A | Direct preparation of pyrrolo [3,4-c] pyrroles | CIBA SC HOLDING AG (CH) | 2000-01-05 | — | — | CN | disclosed |
| CN-1221417-A | Thiazolidinedione compounds having antidiabetic, hypolipidemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | REDDY RESEARCH FOUNDATION (IN) | 1999-06-30 | — | — | CN | disclosed |
| CN-1221415-A | Novel antidiabetic compounds having hypolipidemic and antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | REDDY RESEARCH FOUNDATION (IN) | 1999-06-30 | — | — | CN | disclosed |