Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19879536 | 1.00 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL31748165 | 1.00 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL19207544 | 1.00 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL19207815 | 0.94 | RIPK1 (0.89) | RIPK1 | |
| SCHEMBL19207816 | 0.94 | RIPK1 (0.89) | RIPK1 | |
| SCHEMBL19228271 | 0.88 | RIPK1 (0.78) | RIPK1 | |
| SCHEMBL19207604 | 0.85 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL19207961 | 0.85 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL19207963 | 0.85 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL19207909 | 0.84 | RIPK1 (1.00) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9896458-B2 | Compounds, compositions and methods | DENALI THERAPEUTICS INC. (US) | 2018-02-20 | — | — | US | disclosed |
| US-9896458-B2 | Compounds, compositions and methods | DENALI THERAPEUTICS INC. (US) | 2018-02-20 | — | — | US | disclosed |