Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.46 |
| ▸ | CYCS | P99999 | 3/20 | 0.45 |
| ▸ | TERT | O14746 | 3/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25703952 | 1.00 | TOP1 (0.46) | TOP1CYCSTERTSTAT3STAT1 | |
| SCHEMBL25705248 | 0.91 | TOP1 (0.45) | TOP1CYCSTERTSTAT3STAT1 | |
| SCHEMBL25703764 | 0.91 | TOP1 (0.54) | TOP1CYCSTERTSTAT3STAT1 | |
| SCHEMBL16978922 | 0.91 | TOP1 (0.54) | TOP1CYCSTERTSTAT3STAT1 | |
| SCHEMBL21577747 | 0.91 | TOP1 (0.54) | TOP1CYCSTERTSTAT3STAT1 | |
| SCHEMBL16978932 | 0.91 | TOP1 (0.54) | TOP1CYCSTERTSTAT3STAT1 | |
| SCHEMBL19879780 | 0.90 | TERT (0.45) | TOP1CYCSTERTENPP2HDAC6 | |
| SCHEMBL1971674 | 0.85 | TERT (0.57) | TOP1CYCSTERTENPP2HDAC6 | |
| SCHEMBL30774963 | 0.85 | TERT (0.57) | TOP1CYCSTERTENPP2HDAC6 | |
| SCHEMBL9429390 | 0.85 | TERT (0.57) | TOP1CYCSTERTENPP2ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9896461-B2 | Polysilylated organosilane compounds | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) (FR) | 2018-02-20 | — | — | US | disclosed |