Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 14/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30890790 | 1.00 | RIPK1 (0.53) | RIPK1KMT2AL3MBTL1SCN9AKDM1A | |
| SCHEMBL19224576 | 1.00 | RIPK1 (0.53) | RIPK1KMT2AL3MBTL1SCN9AKDM1A | |
| SCHEMBL19207938 | 1.00 | RIPK1 (0.53) | RIPK1KMT2AL3MBTL1SCN9AKDM1A | |
| SCHEMBL19228382 | 1.00 | RIPK1 (0.53) | RIPK1KMT2AL3MBTL1SCN9AKDM1A | |
| SCHEMBL19228384 | 1.00 | RIPK1 (0.53) | RIPK1KMT2AL3MBTL1SCN9AKDM1A | |
| SCHEMBL19228387 | 1.00 | RIPK1 (0.53) | RIPK1KMT2AL3MBTL1SCN9AKDM1A | |
| SCHEMBL24991617 | 1.00 | RIPK1 (0.53) | RIPK1KMT2AL3MBTL1SCN9AKDM1A | |
| SCHEMBL19224577 | 1.00 | RIPK1 (0.53) | RIPK1KMT2AL3MBTL1SCN9AKDM1A | |
| SCHEMBL19255505 | 1.00 | RIPK1 (0.53) | RIPK1KMT2AL3MBTL1SCN9AKDM1A | |
| SCHEMBL20050170 | 0.86 | RIPK1 (0.45) | RIPK1KMT2AL3MBTL1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9896458-B2 | Compounds, compositions and methods | DENALI THERAPEUTICS INC. (US) | 2018-02-20 | — | — | US | disclosed |