Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24990747 | 0.83 | RIPK1 (0.59) | RIPK1 | |
| SCHEMBL29415652 | 0.82 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL19207965 | 0.82 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL19224688 | 0.82 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL19207964 | 0.82 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL22509158 | 0.81 | RIPK1 (0.55) | RIPK1 | |
| SCHEMBL22509073 | 0.80 | RIPK1 (0.71) | RIPK1 | |
| SCHEMBL19805549 | 0.78 | RIPK1 (0.72) | RIPK1 | |
| SCHEMBL19228622 | 0.76 | RIPK1 (0.72) | RIPK1 | |
| SCHEMBL24991793 | 0.76 | RIPK1 (0.42) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9896458-B2 | Compounds, compositions and methods | DENALI THERAPEUTICS INC. (US) | 2018-02-20 | — | — | US | disclosed |