Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 3/20 | 0.45 |
| ▸ | LATS2 | Q9NRM7 | 3/20 | 0.45 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.33 |
| ▸ | CLK1 | P49759 | 2/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15644598 | 0.87 | LATS1 (0.44) | LATS1LATS2 | |
| SCHEMBL16908288 | 0.82 | LATS1 (0.59) | LATS1LATS2 | |
| SCHEMBL30065225 | 0.82 | LATS1 (0.59) | LATS1LATS2 | |
| SCHEMBL15645107 | 0.74 | S1PR1 (0.43) | LATS1LATS2 | |
| SCHEMBL15646156 | 0.71 | LATS1 (0.44) | LATS1LATS2 | |
| SCHEMBL30291339 | 0.71 | LATS1 (0.35) | LATS1LATS2 | |
| SCHEMBL15644972 | 0.71 | CYP17A1 (0.34) | LATS1LATS2 | |
| SCHEMBL20547439 | 0.67 | LATS1 (0.62) | LATS1LATS2 | |
| SCHEMBL24746836 | 0.67 | CDC7 (0.47) | LATS1LATS2 | |
| SCHEMBL30064150 | 0.67 | CDC7 (0.47) | LATS1LATS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9896446-B2 | Azaquinazoline inhibitors of atypical protein kinase C | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2018-02-20 | — | — | US | disclosed |