Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 2/20 | 0.35 |
| ▸ | LATS2 | Q9NRM7 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16908274 | 0.75 | PDE4A (0.38) | — | |
| SCHEMBL29344431 | 0.74 | PARP1 (0.47) | — | |
| SCHEMBL16908288 | 0.71 | LATS1 (0.59) | LATS1LATS2 | |
| SCHEMBL30065225 | 0.71 | LATS1 (0.59) | LATS1LATS2 | |
| SCHEMBL19880933 | 0.71 | LATS1 (0.45) | LATS1LATS2 | |
| SCHEMBL15644598 | 0.66 | LATS1 (0.44) | LATS1LATS2 | |
| SCHEMBL21361036 | 0.66 | — | — | |
| SCHEMBL16908309 | 0.64 | CDC7 (0.41) | LATS1LATS2 | |
| SCHEMBL2490205 | 0.63 | — | — | |
| SCHEMBL10726274 | 0.62 | CYP3A4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115785088-A | Compounds as SOS1 inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2023-03-14 | — | — | CN | disclosed |