Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 5/20 | 0.51 |
| ▸ | PPIB | P23284 | 5/20 | 0.50 |
| ▸ | PPIG | Q13427 | 2/20 | 0.50 |
| ▸ | PPIA | P62937 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2042414 | 0.89 | PPID (0.64) | PPIDPPIBPPIGPPIAALDH1A1 | |
| SCHEMBL2039017 | 0.82 | PPID (0.67) | PPIDPPIBPPIGPPIA | |
| SCHEMBL12643703 | 0.80 | PPID (0.60) | PPIDPPIBPPIGPPIAALDH1A1 | |
| SCHEMBL19882150 | 0.76 | PPID (0.58) | PPIDPPIBPPIGPPIAALDH1A1 | |
| SCHEMBL12643698 | 0.73 | PPID (0.63) | PPIDPPIBPPIGPPIA | |
| SCHEMBL16270322 | 0.70 | PPID (0.81) | PPIDPPIBPPIGPPIAALDH1A1 | |
| SCHEMBL14617663 | 0.68 | PPID (0.78) | PPIDPPIBPPIGPPIAALDH1A1 | |
| SCHEMBL19882131 | 0.68 | PPIB (0.53) | PPIDPPIBKMT2AMEN1L3MBTL1 | |
| SCHEMBL20642216 | 0.68 | CYP4F2 (0.68) | NAMPTMAPTEPHX2MAPK1 | |
| SCHEMBL2034522 | 0.67 | PPID (0.76) | PPIDPPIBPPIGPPIAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516387-B1 | INHIBITORS OF CYCLOPHILINS FOR USE IN THE PREVENTION AND/OR THE TREATMENT OF VIRAL PATHOLOGIES OR INFECTIONS | INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECH MÉDICALE (INSERM) (FR) | 2018-02-21 | — | — | EP | disclosed |