Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 9/20 | 0.60 |
| ▸ | PPIB | P23284 | 5/20 | 0.60 |
| ▸ | PPIG | Q13427 | 2/20 | 0.60 |
| ▸ | PPIA | P62937 | 1/20 | 0.60 |
| ▸ | TNF | P01375 | 2/20 | 0.35 |
| ▸ | CYP4Z1 | Q86W10 | 2/20 | 0.35 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.35 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12643698 | 0.94 | PPID (0.63) | PPIDPPIBPPIGPPIA | |
| SCHEMBL2042414 | 0.91 | PPID (0.64) | PPIDPPIBPPIGPPIATNF | |
| SCHEMBL2039017 | 0.85 | PPID (0.67) | PPIDPPIBPPIGPPIA | |
| SCHEMBL19882152 | 0.80 | PPID (0.51) | PPIDPPIBPPIGPPIAGAA | |
| SCHEMBL2044119 | 0.77 | PPID (1.00) | PPIDPPIBPPIGPPIAALDH1A1 | |
| SCHEMBL12643704 | 0.77 | PPID (0.64) | PPIDPPIBPPIGPPIAGAA | |
| SCHEMBL12643694 | 0.77 | PPID (0.61) | PPIDPPIBPPIGPPIAMAPK1 | |
| SCHEMBL12643701 | 0.74 | PPID (0.60) | PPIDPPIBPPIGPPIANPSR1 | |
| SCHEMBL12643831 | 0.70 | PPIB (0.51) | PPIDPPIBPPIGPPIAGAA | |
| SCHEMBL12643824 | 0.70 | PPID (1.00) | PPIDPPIBPPIGPPIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011076784-A2 | NEW INHIBITORS OF CYCLOPHILINS AND USES THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2011-06-30 | — | — | WO | disclosed |