Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 10/20 | 0.52 |
| ▸ | PPIG | Q13427 | 4/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PPIB | P23284 | 2/20 | 0.40 |
| ▸ | PPIA | P62937 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2040765 | 0.69 | PPID (1.00) | PPIDPPIGCTSLCTSBCTSS | |
| SCHEMBL14575948 | 0.69 | PPIB (0.62) | PPIDPPIGCTSLCTSBCTSS | |
| SCHEMBL2038175 | 0.68 | PPID (1.00) | PPIDPPIGPPIBPPIA | |
| SCHEMBL12643631 | 0.67 | PPID (0.80) | PPIDPPIGCTSLCTSBCTSS | |
| SCHEMBL4139513 | 0.65 | ANPEP (0.75) | PPIDCTSLCTSBCTSSCTSK | |
| SCHEMBL4770866 | 0.65 | ANPEP (0.79) | CTSLCTSBCTSSCTSKANPEP | |
| SCHEMBL4770883 | 0.65 | ANPEP (0.79) | CTSLCTSBCTSSCTSKANPEP | |
| SCHEMBL14576521 | 0.64 | PPID (0.53) | PPIDANPEPPPIB | |
| SCHEMBL14575949 | 0.63 | PPIB (0.50) | PPIDPPIGCTSLCTSBCTSS | |
| SCHEMBL19882151 | 0.62 | ANPEP (0.49) | PPIDCTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516387-B1 | INHIBITORS OF CYCLOPHILINS FOR USE IN THE PREVENTION AND/OR THE TREATMENT OF VIRAL PATHOLOGIES OR INFECTIONS | INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECH MÉDICALE (INSERM) (FR) | 2018-02-21 | — | — | EP | disclosed |