Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.49 |
| ▸ | ITGAV | P06756 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2036911 | 0.92 | ITGB3 (0.58) | ITGB3ITGAVMAPTKLK7KLK5 | |
| SCHEMBL12643650 | 0.88 | MAPT (0.48) | MAPTCTSKKDM4ETDP1GLA | |
| SCHEMBL18942686 | 0.83 | KLK7 (0.65) | ITGB3MAPTKLK7KLK5SIRT2 | |
| SCHEMBL3182565 | 0.80 | NAMPT (0.57) | MAPTKDM4ETDP1NPSR1MEN1 | |
| SCHEMBL12643655 | 0.80 | MAPT (0.51) | ITGB3ITGAVMAPTKDM4ETDP1 | |
| SCHEMBL14576371 | 0.80 | MAPT (0.51) | ITGB3ITGAVMAPTKDM4ETDP1 | |
| SCHEMBL2053665 | 0.80 | MAPT (0.51) | ITGB3ITGAVMAPTKDM4ETDP1 | |
| SCHEMBL31294223 | 0.80 | MAPT (0.54) | ITGB3MAPTKLK7KLK5SIRT2 | |
| SCHEMBL2036189 | 0.79 | CA1 (0.48) | ITGB3ITGAVMAPTFOLH1CTSK | |
| SCHEMBL16124431 | 0.79 | MAPT (0.60) | ITGB3MAPTKLK7KLK5CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516387-B1 | INHIBITORS OF CYCLOPHILINS FOR USE IN THE PREVENTION AND/OR THE TREATMENT OF VIRAL PATHOLOGIES OR INFECTIONS | INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECH MÉDICALE (INSERM) (FR) | 2018-02-21 | — | — | EP | disclosed |