Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 2/20 | 0.71 |
| ▸ | PPIB | P23284 | 1/20 | 0.49 |
| ▸ | PRMT3 | O60678 | 8/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.44 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15832157 | 0.86 | PPID (0.75) | PPIDPPIBRAB9AALDH1A1AVPR2 | |
| SCHEMBL15832190 | 0.85 | PPID (0.73) | PPIDPPIBRAB9AALDH1A1AVPR2 | |
| SCHEMBL2037719 | 0.83 | PPID (1.00) | PPIDPPIBRAB9A | |
| SCHEMBL2053173 | 0.82 | PPID (0.97) | PPIDPPIBRAB9A | |
| SCHEMBL15832159 | 0.75 | PPID (0.59) | PPIDPPIBRAB9AALDH1A1 | |
| SCHEMBL16270323 | 0.74 | PPID (0.57) | PPIDPPIBRAB9AALDH1A1POLB | |
| SCHEMBL14617671 | 0.73 | PPIB (0.64) | PPIDPPIBRAB9AALDH1A1POLB | |
| SCHEMBL14617668 | 0.73 | PPIB (0.59) | PPIDPPIBRAB9AALDH1A1POLB | |
| SCHEMBL23135311 | 0.73 | NPC1 (0.39) | PPIDNAMPTRAB9AALDH1A1POLB | |
| SCHEMBL2038271 | 0.72 | PPID (0.78) | PPIDPPIB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516387-B1 | INHIBITORS OF CYCLOPHILINS FOR USE IN THE PREVENTION AND/OR THE TREATMENT OF VIRAL PATHOLOGIES OR INFECTIONS | INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECH MÉDICALE (INSERM) (FR) | 2018-02-21 | — | — | EP | disclosed |