SCHEMBL23135311

SCHEMBL23135311

CNc1ccc(CNC(=N)N2CCC2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 5/20 0.39
▸ RAB9A P51151 4/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ KMT2A Q03164 2/20 0.37
▸ PPID Q08752 1/20 0.37
▸ ALDH1A1 P00352 1/20 0.36
▸ MAPT P10636 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ NAMPT P43490 2/20 0.36
▸ EPHX2 P34913 1/20 0.36
▸ NCF1 P14598 2/20 0.36
▸ GAA P10253 1/20 0.35
▸ TPSAB1 Q15661 1/20 0.35
▸ TPSD1 Q9BZJ3 1/20 0.35
▸ TPSG1 Q9NRR2 1/20 0.35
▸ CHRM1 P11229 1/20 0.35
▸ HTR2A P28223 1/20 0.35
▸ MCHR1 Q99705 1/20 0.35
▸ POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23135415 0.90 RAB9A (0.36) NPC1RAB9ASMN1; SMN2KMT2APPID
SCHEMBL23135417 0.81 PPID (0.55) PPIDALDH1A1EPHX2TPSAB1TPSD1
SCHEMBL26158515 0.79 HRH3 (0.42) RAB9ASMN1; SMN2ALDH1A1MAPT
SCHEMBL23135392 0.73 ADRA2A (0.41) NPC1RAB9ASMN1; SMN2ALDH1A1TPSAB1
SCHEMBL23135383 0.73 PPID (0.50) PPIDALDH1A1EPHX2TPSAB1TPSD1
SCHEMBL19882168 0.73 PPID (0.71) RAB9APPIDALDH1A1NAMPTPOLB
SCHEMBL14703240 0.72 MEN1 (0.46) NPC1RAB9ASMN1; SMN2KMT2AALDH1A1
SCHEMBL23135376 0.70 NPC1 (0.38) NPC1RAB9ASMN1; SMN2ALDH1A1EPHX2
SCHEMBL14703438 0.70 KCNH2 (0.42) SMN1; SMN2KMT2AALDH1A1MAPTMEN1
SCHEMBL14703246 0.70 SMN1; SMN2 (0.44) NPC1RAB9ASMN1; SMN2KMT2APPID

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230264171-A1 CHROMATOGRAPHY RESIN HAVING AN ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE LIGAND BIO-RAD LABORATORIES, INC. 2023-08-24 — — US disclosed
US-20230264171-A1 CHROMATOGRAPHY RESIN HAVING AN ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE LIGAND BIO-RAD LABORATORIES, INC. 2023-08-24 — — US disclosed
US-11666888-B2 Chromatography resin having an anionic exchange-hydrophobic mixed mode ligand BIO-RAD LABORATORIES, INC. (US) 2023-06-06 — — US disclosed
US-11666888-B2 Chromatography resin having an anionic exchange-hydrophobic mixed mode ligand BIO-RAD LABORATORIES, INC. (US) 2023-06-06 — — US disclosed
US-20210086165-A1 CHROMATOGRAPHY RESIN HAVING AN ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE LIGAND BIO-RAD LABORATORIES, INC. 2021-03-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11666888-B2 Chromatography resin having an anionic exchange-hydrophobic mixed mode ligand MSR1, RXRA, MLX NPC1 1303/4885RAB9A 2059/4885SMN1; SMN2 4015/4885
US-20230264171-A1 CHROMATOGRAPHY RESIN HAVING AN ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE LIGAND MSR1, RXRA, MLX NPC1 1303/4885RAB9A 2059/4885SMN1; SMN2 4015/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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