Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 4/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20003203 | 0.93 | RARB (0.39) | ELANERARBFAAHKMT2AATM | |
| SCHEMBL9607895 | 0.91 | ELANE (0.47) | ELANEKMT2AATMAPPCYP2C19 | |
| SCHEMBL19624089 | 0.91 | THRB (0.45) | ELANERARBRARAKMT2AATM | |
| SCHEMBL19214246 | 0.90 | RARB (0.35) | ELANERARBFAAHRARAAPP | |
| SCHEMBL16140695 | 0.88 | ELANE (0.39) | ELANERARBRARAKMT2AATM | |
| SCHEMBL16436111 | 0.88 | ELANE (0.39) | ELANERARBRARAKMT2AATM | |
| SCHEMBL20925166 | 0.88 | KMT2A (0.40) | ELANERARBRARAKMT2AATM | |
| SCHEMBL10020856 | 0.87 | RARB (0.44) | ELANERARBFAAHRARAKMT2A | |
| SCHEMBL21483214 | 0.86 | RARB (0.38) | ELANERARBRARAKMT2AATM | |
| SCHEMBL21483174 | 0.86 | RARB (0.38) | ELANERARBRARAKMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3083408-B1 | FILLING DEVICE AND USE THEREOF FOR FILLING A FLUID | MERCK PATENT GMBH (DE) | 2018-02-21 | — | — | EP | disclosed |