SCHEMBL19882280

SCHEMBL19882280

Cc1cc2c(c(F)c1F)CC(CCC1CCc3c(cc(F)c(C)c3F)C1)CC2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22137709 1.00
SCHEMBL23240318 0.85
SCHEMBL21577511 0.83
SCHEMBL802798 0.79
SCHEMBL22508506 0.74
SCHEMBL6159162 0.72 FYN (0.38)
SCHEMBL18137123 0.72
SCHEMBL6159029 0.72 FYN (0.38)
SCHEMBL24513479 0.72
SCHEMBL16433525 0.71 MAPT (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11802243-B2 Liquid-crystal medium MERCK PATENT GMBH (DE) 2023-10-31 US disclosed
US-20230295510-A1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2023-09-21 US disclosed
US-20230295511-A1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2023-09-21 US disclosed
US-11739265-B2 Aromatic isothiocyanates MERCK PATENT GMBH (DE) 2023-08-29 US disclosed
US-20230025385-A1 FLUORINATED AROMATIC COMPOUNDS MERCK PATENT GMBH (DE) 2023-01-26 US disclosed
US-11370969-B2 Liquid-crystal medium MERCK PATENT GMBH (DE) 2022-06-28 US disclosed
EP-3985085-A2 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2022-04-20 EP disclosed
US-20200347301-A1 Isothiocyanato-tolanes MERCK PATENT GMBH (DE) 2020-11-05 US disclosed
EP-2881383-B1 Mixing device and its use MERCK PATENT GMBH (DE) 2020-06-24 EP disclosed
EP-3628721-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2020-04-01 EP disclosed
US-20190345389-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2019-11-14 US disclosed
EP-3083883-B1 METHOD FOR CLEANING A LIQUID CRYSTAL MIXTURE MERCK PATENT GMBH (DE) 2018-07-11 EP disclosed
EP-3083408-B1 FILLING DEVICE AND USE THEREOF FOR FILLING A FLUID MERCK PATENT GMBH (DE) 2018-02-21 EP disclosed