SCHEMBL23240318

SCHEMBL23240318

Cc1c(F)cc2c(c1F)CCC(CCC1CCc3cc(-c4cc5c(c(F)c4F)CC(C)CC5)c(F)c(F)c3C1)C2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21115668 0.89
SCHEMBL22508506 0.87
SCHEMBL22137709 0.85
SCHEMBL19882280 0.85
SCHEMBL12976105 0.78 ALDH1A1 (0.38)
SCHEMBL21096538 0.78 CYP2A6 (0.33)
SCHEMBL18137123 0.73
SCHEMBL18137132 0.70
SCHEMBL24513479 0.70
SCHEMBL802798 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3933009-B1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2023-08-16 EP disclosed
EP-3839008-B1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2023-07-26 EP disclosed
WO-2022106387-A1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2022-05-27 WO disclosed
WO-2022090099-A1 AROMATIC ISOTHIOCYANATES MERCK PATENT GMBH (DE) 2022-05-05 WO disclosed
WO-2022043376-A1 AROMATIC ISOTHIOCYANATES MERCK PATENT GMBH (DE) 2022-03-03 WO disclosed
WO-2022008474-A1 OPTICAL COMPONENT MERCK PATENT GMBH (DE) 2022-01-13 WO disclosed
WO-2022003001-A1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2022-01-06 WO disclosed
EP-3933009-A1 LIQUID CRYSTAL MEDIUM Merck Patent GmbH (DE) 2022-01-05 EP disclosed
EP-3839008-A1 LIQUID CRYSTAL MEDIUM Merck Patent GmbH (DE) 2021-06-23 EP disclosed
WO-2021069535-A1 FLUORINATED AROMATIC COMPOUNDS MERCK PATENT GMBH (DE) 2021-04-15 WO disclosed