Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 3/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TPSAB1 | Q15661 | 4/20 | 0.31 |
| ▸ | TPSD1 | Q9BZJ3 | 4/20 | 0.31 |
| ▸ | TPSG1 | Q9NRR2 | 4/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | RBP4 | P02753 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17663698 | 0.85 | KMT2A (0.50) | BTKNAMPTKMT2ALMNA | |
| SCHEMBL19886208 | 0.81 | BTK (0.36) | BTKNAMPTKMT2A | |
| SCHEMBL17664667 | 0.79 | POLB (0.45) | BTKATMNR1H2RBP4 | |
| SCHEMBL17660260 | 0.75 | SMN1; SMN2 (0.42) | BTKKMT2A | |
| SCHEMBL20026858 | 0.74 | ATM (0.41) | BTKATMNR1H2 | |
| SCHEMBL20054041 | 0.74 | BTK (0.37) | BTK | |
| SCHEMBL21165813 | 0.73 | CHRNB2 (0.48) | NAMPTATMNR1H2 | |
| SCHEMBL11998894 | 0.72 | CHRNB2 (0.43) | ATMNR1H2 | |
| SCHEMBL2937689 | 0.72 | ATM (0.34) | ATMNR1H2RBP4 | |
| SCHEMBL17663700 | 0.72 | EPHX2 (0.35) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018035080-A1 | 2-OXO-IMIDAZOPYRIDINES AS REVERSIBLE BTK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2018-02-22 | — | — | WO | disclosed |