Pyridine

Pyridine

SCHEMBL1989293

Sc1cc(Cl)c(Cl)c(Cl)c1Cl.c1ccncc1

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.40
TSHR P16473 2/20 0.38
NAPRT Q6XQN6 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
HSP90AA1 P07900 1/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33
RHEB Q15382 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL48413 0.82 CYP3A4 (0.59) CYP3A4TSHRHSP90AA1HPGDHSD17B10
SCHEMBL4229727 0.79 CYP3A4 (0.56) CYP3A4TSHRHSP90AA1HPGDHSD17B10
Pyridine SCHEMBL28297009 0.68
Pyridine SCHEMBL28046997 0.66 TDP1 (0.47) TSHRNAPRTTDP1HPGD
Pentachlorophenol SCHEMBL11231001 0.66 TSHR (0.53) CYP3A4TSHRNAPRTTDP1HPGD
Pyridine SCHEMBL27362811 0.65
Pyridine SCHEMBL31396433 0.65
Pyridine SCHEMBL1629374 0.65 TSHR (0.90) CYP3A4TSHRNAPRTTDP1
Pyridine SCHEMBL11040344 0.65
SCHEMBL9643509 0.64 CYP3A4 (0.47) CYP3A4TSHRHSP90AA1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150165275-A1 INJECTION MOLDABLE COMPOSITIONS AND GOLF BALLS PREPARED THEREFROM TAYLOR MADE GOLF COMPANY, INC. (US) 2015-06-18 US disclosed
US-8992341-B2 Injection moldable compositions and golf balls prepared therefrom TAYLOR MADE GOLF COMPANY, INC. (US) 2015-03-31 US disclosed
US-20110152008-A1 INJECTION MOLDABLE COMPOSITIONS AND GOLF BALLS PREPARED THEREFROM TAYLOR MADE GOLF COMPANY, INC. 2011-06-23 US disclosed