Pyridine

Pyridine

SCHEMBL28046997

Clc1nc(Cl)c(Cl)c(Cl)c1Cl.c1ccncc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.47
TSHR P16473 1/20 0.47
NAPRT Q6XQN6 1/20 0.47
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
LMNA P02545 1/20 0.33
NPC1 O15118 1/20 0.33
METAP1 P53582 1/20 0.33
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
CYP2A6 P11509 1/20 0.31
CCR1 P32246 1/20 0.31
CCR5 P51681 1/20 0.31
CCR8 P51685 1/20 0.31
NOTUM Q6P988 1/20 0.31
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL28297009 0.76
SCHEMBL468366 0.76 ALDH1A1 (0.36) TDP1TSHRMEN1KMT2ALMNA
Pentachlorophenol SCHEMBL11231001 0.74 TSHR (0.53) TDP1TSHRNAPRTMEN1KMT2A
Ammonia Solution, Strong SCHEMBL9646819 0.73 ALDH1A1 (0.43) TSHRALDH1A1
Hydrochloric Acid SCHEMBL27691899 0.73 ALDH1A1 (0.33) TSHRALDH1A1
SCHEMBL9647771 0.73 ALDH1A1 (0.33) TSHRALDH1A1
Potassium SCHEMBL8421932 0.73 ALDH1A1 (0.33) TSHRALDH1A1
Pyridine SCHEMBL31396433 0.72
Pyridine SCHEMBL27324424 0.72 TSHR (0.45) TDP1TSHRNAPRT
Pyridine SCHEMBL11202224 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105237471-A Method for preparing pentachloropyridine from DCTF rectifying short steaming residues YANCHENG INST TECHNOLOGY 2016-01-13 CN claimed
CN-109734657-A A kind of preparation method of 2,3,6- trichloropyridine 重庆中邦科技有限公司 2019-05-10 CN disclosed
CN-1657164-A Catalyst for preparing penta chloropyridine and its preparation method UNIV SOUTHEAST (CN) 2005-08-24 CN disclosed