Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.42 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15593268 | 1.00 | BTN3A1 (0.49) | BTN3A1TP53ELANEPRTN3KLK1 | |
| SCHEMBL22105334 | 0.94 | BTN3A1 (0.53) | BTN3A1TP53ELANEPRTN3KLK1 | |
| SCHEMBL22105034 | 0.94 | BTN3A1 (0.53) | BTN3A1TP53ELANEPRTN3KLK1 | |
| SCHEMBL18973504 | 0.94 | BTN3A1 (0.53) | BTN3A1TP53ELANEPRTN3KLK1 | |
| SCHEMBL18953088 | 0.94 | BTN3A1 (0.53) | BTN3A1TP53ELANEPRTN3KLK1 | |
| SCHEMBL18973471 | 0.92 | TP53 (0.56) | BTN3A1TP53ELANEPRTN3KLK1 | |
| SCHEMBL24148685 | 0.88 | BTN3A1 (0.51) | BTN3A1ELANEPRTN3KLK1NPC1 | |
| SCHEMBL16576028 | 0.86 | BTN3A1 (0.50) | BTN3A1TP53ELANEPRTN3KLK1 | |
| SCHEMBL16576035 | 0.86 | BTN3A1 (0.50) | BTN3A1TP53ELANEPRTN3KLK1 | |
| SCHEMBL15756840 | 0.86 | BTN3A1 (0.42) | BTN3A1ALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2890704-B1 | 2'-ETHYNYL NUCLEOSIDE DERIVATIVES FOR TREATMENT OF VIRAL INFECTIONS | NOVARTIS AG (CH) | 2018-02-28 | — | — | EP | disclosed |