Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | BTN3A1 | O00481 | 3/20 | 0.55 |
| ▸ | ELANE | P08246 | 2/20 | 0.51 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KLK1 | P06870 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16576028 | 0.94 | BTN3A1 (0.50) | TP53BTN3A1ELANEPRTN3NPC1 | |
| SCHEMBL16576035 | 0.94 | BTN3A1 (0.50) | TP53BTN3A1ELANEPRTN3NPC1 | |
| SCHEMBL16576019 | 0.94 | BTN3A1 (0.50) | TP53BTN3A1ELANEPRTN3NPC1 | |
| SCHEMBL24505391 | 0.92 | BTN3A1 (0.60) | TP53BTN3A1ELANEPRTN3KLK1 | |
| SCHEMBL18973549 | 0.92 | BTN3A1 (0.60) | TP53BTN3A1ELANEPRTN3KLK1 | |
| SCHEMBL19894592 | 0.92 | BTN3A1 (0.49) | TP53BTN3A1ELANEPRTN3NPC1 | |
| SCHEMBL15593268 | 0.92 | BTN3A1 (0.49) | TP53BTN3A1ELANEPRTN3NPC1 | |
| SCHEMBL28918364 | 0.89 | TP53 (0.52) | TP53BTN3A1ELANEPRTN3NPC1 | |
| SCHEMBL12621325 | 0.89 | TP53 (0.52) | TP53BTN3A1ELANEPRTN3NPC1 | |
| SCHEMBL22065043 | 0.89 | BTN3A1 (0.47) | TP53BTN3A1ELANEPRTN3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220402962-A1 | SYNTHESIS OF PHOSPHATE DERIVATIVES | NuCana plc (GB) | 2022-12-22 | — | — | US | disclosed |
| US-20210009625-A1 | DIASTEREOSELECTIVE SYNTHESIS OF PHOSPHATE DERIVATIVES | LAURUS LABS PRIVATE LTD (IN) | 2021-01-14 | — | — | US | disclosed |
| US-10774104-B2 | Diastereoselective synthesis of phosphate derivatives | LAURUS LABS PRIVATE LTD (IN) | 2020-09-15 | — | — | US | disclosed |
| US-20200181186-A1 | SYNTHESIS OF PHOSPHATE DERIVATIVES | NuCana plc (GB) | 2020-06-11 | — | — | US | disclosed |
| US-20200181190-A1 | SYNTHESIS OF 3'-DEOXYADENOSINE-5'-O-[PHENYL(BENZYLOXY-L-ALANINYL)]PHOSPHATE (NUC-7738) | NuCana plc (GB) | 2020-06-11 | — | — | US | disclosed |
| WO-2017098252-A1 | DIASTEREOSELECTIVE SYNTHESIS OF PHOSPHATE DERIVATIVES AND OF THE GEMCITABINE PRODRUG NUC-1031 | NUCANA BIOMED LIMITED (GB) | 2017-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10774104-B2 | Diastereoselective synthesis of phosphate derivatives | TYMP, PNP, DPYD | TP53 658/4885BTN3A1 4678/4885ELANE 4526/4885 |
| US-20200181186-A1 | SYNTHESIS OF PHOSPHATE DERIVATIVES | PPA1, PPIP5K2, TYMP | TP53 100/4885BTN3A1 4531/4885ELANE 4653/4885 |
| US-20220402962-A1 | SYNTHESIS OF PHOSPHATE DERIVATIVES | PNP, NTPCR, TYMP | TP53 926/4885BTN3A1 2948/4885ELANE 3870/4885 |
| US-20210009625-A1 | DIASTEREOSELECTIVE SYNTHESIS OF PHOSPHATE DERIVATIVES | TYMP, PNP, DPYD | TP53 522/4885BTN3A1 4228/4885ELANE 4731/4885 |
| US-20200181190-A1 | SYNTHESIS OF 3'-DEOXYADENOSINE-5'-O-[PHENYL(BENZYLOXY-L-ALANINYL)]PHOSPHATE (NUC-7738) | PNP, NT5C2, DUT | TP53 755/4885BTN3A1 3995/4885ELANE 3725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.