Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28468343 | 0.95 | ESR1 (0.48) | ESR1CA2CA4CA5AALDH1A1 | |
| SCHEMBL191537 | 0.95 | ESR1 (0.48) | ESR1CA2CA4CA5AALDH1A1 | |
| SCHEMBL191017 | 0.95 | ESR1 (0.48) | ESR1CA2CA4CA5AALDH1A1 | |
| Zinc Ion SCHEMBL191600 | 0.95 | ESR1 (0.48) | ESR1CA2CA4CA5AALDH1A1 | |
| SCHEMBL190560 | 0.95 | ESR1 (0.48) | ESR1CA2CA4CA5AALDH1A1 | |
| SCHEMBL28610141 | 0.95 | ESR1 (0.48) | ESR1CA2CA4CA5AALDH1A1 | |
| SCHEMBL345377 | 0.80 | HPGD (0.43) | ESR1GAATSHRHPGD | |
| SCHEMBL345473 | 0.80 | HPGD (0.43) | ESR1GAATSHRHPGD | |
| SCHEMBL345062 | 0.80 | HPGD (0.43) | ESR1GAATSHRHPGD | |
| Zinc Ion SCHEMBL344701 | 0.80 | HPGD (0.43) | ESR1GAATSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180057685-A1 | FLAME-RETARDANT RESIN COMPOSITION | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2018-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180057685-A1 | FLAME-RETARDANT RESIN COMPOSITION | PRPF4, RPL4, PSMB4 | ESR1 1837/4885CA2 4754/4885CA4 2930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.