SCHEMBL19896380

SCHEMBL19896380

CCCCCCCC(c1ccccc1)n1c2cc(N=C(c3ccccc3)c3ccccc3)ccc2c2ccc(N=C(c3ccccc3)c3ccccc3)cc21

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ OPRM1 P35372 8/20 0.40
▸ OPRD1 P41143 8/20 0.40
▸ OPRK1 P41145 8/20 0.40
▸ OPRL1 P41146 8/20 0.40
▸ BRD4 O60885 1/20 0.39
▸ CNR2 P34972 1/20 0.33
▸ PSEN1 P49768 3/20 0.32
▸ PSEN2 P49810 3/20 0.32
▸ APH1B Q8WW43 3/20 0.32
▸ NCSTN Q92542 3/20 0.32
▸ APH1A Q96BI3 3/20 0.32
▸ PSENEN Q9NZ42 3/20 0.32
▸ PTGS2 P35354 1/20 0.32
▸ PKM P14618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19896310 1.00 OPRM1 (0.40) OPRM1OPRD1OPRK1OPRL1BRD4
SCHEMBL19896318 0.82 CNR2 (0.34) OPRD1BRD4CNR2PTGS2
SCHEMBL19896353 0.79 CNR2 (0.50) CNR2PSEN1PSEN2APH1BNCSTN
SCHEMBL19896356 0.79 CNR2 (0.50) CNR2PSEN1PSEN2APH1BNCSTN
SCHEMBL19896452 0.79 CNR2 (0.50) CNR2PSEN1PSEN2APH1BNCSTN
SCHEMBL19896433 0.77 OPRM1 (0.43) OPRM1OPRD1OPRK1OPRL1BRD4
SCHEMBL19896280 0.77 OPRM1 (0.43) OPRM1OPRD1OPRK1OPRL1BRD4
SCHEMBL19896308 0.77 BRD4 (0.38) BRD4
Hydrochloric Acid SCHEMBL19896361 0.76 OPRM1 (0.42) OPRM1OPRD1OPRK1OPRL1BRD4
Hydrochloric Acid SCHEMBL19896410 0.76 OPRM1 (0.42) OPRM1OPRD1OPRK1OPRL1BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10421779-B2 Carbazole compound having anti-virus activity KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2019-09-24 — — US disclosed
US-20180057527-A1 CARBAZOLE COMPOUND HAVING ANTI-VIRUS ACTIVITY KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2018-03-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180057527-A1 CARBAZOLE COMPOUND HAVING ANTI-VIRUS ACTIVITY ZC3HAV1, ZC3HAV1L, GTF3C3 OPRM1 4146/4885OPRD1 3087/4885OPRK1 2750/4885
US-10421779-B2 Carbazole compound having anti-virus activity ZC3HAV1, ZC3HAV1L, GTF3C3 OPRM1 4146/4885OPRD1 3087/4885OPRK1 2750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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