Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | AGXT | P21549 | 2/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3125403 | 0.79 | IDO1 (0.47) | IDO1AGXTABCC4LMNAGAA | |
| SCHEMBL2221138 | 0.79 | SLC16A3 (0.53) | IDO1AGXTABCC4LMNAGAA | |
| SCHEMBL2259215 | 0.79 | — | — | |
| SCHEMBL27657693 | 0.76 | ALDH1A1 (0.50) | TSHRKMT2A | |
| SCHEMBL27657695 | 0.76 | ALDH1A1 (0.50) | TSHRKMT2A | |
| Boric Acid SCHEMBL28083957 | 0.76 | IDO1 (0.44) | IDO1AGXT | |
| SCHEMBL10819593 | 0.76 | IDO1 (0.55) | IDO1AGXT | |
| SCHEMBL17750774 | 0.76 | IDO1 (0.39) | IDO1AGXTLMNA | |
| SCHEMBL11654721 | 0.74 | ABCC4 (0.42) | IDO1AGXTABCC4LMNAGAA | |
| SCHEMBL18661930 | 0.73 | IDO1 (0.57) | IDO1AGXTABCC4LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334636-A2 | HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | Pfizer Inc. (US) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010032147-A2 | HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2010-03-25 | — | — | WO | disclosed |