Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 3/20 | 0.30 |
| ▸ | RAB9A | P51151 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30826320 | 0.85 | KDM4E (0.54) | MAPTCYP3A4CYP2D6CYP2C9KDM4E | |
| SCHEMBL10313033 | 0.85 | BAZ2B (0.42) | CHEK1CHEK2NPSR1BAZ2BHTT | |
| SCHEMBL12395230 | 0.85 | BAZ2B (0.42) | CHEK1CHEK2NPSR1BAZ2BHTT | |
| SCHEMBL6370890 | 0.85 | BAZ2B (0.42) | CHEK1CHEK2NPSR1BAZ2BHTT | |
| SCHEMBL2597584 | 0.84 | CHEK1 (0.42) | MAPTKDM4ECHEK1CHEK2BAZ2B | |
| SCHEMBL12185503 | 0.84 | CHEK1 (0.42) | MAPTKDM4ECHEK1CHEK2BAZ2B | |
| SCHEMBL14207868 | 0.83 | CHEK1 (0.40) | CHEK1CHEK2BAZ2BHTTTSHR | |
| SCHEMBL14207870 | 0.81 | CHEK1 (0.39) | CHEK1CHEK2BAZ2BHTTTSHR | |
| SCHEMBL19917643 | 0.81 | BAZ2B (0.35) | CHEK1CHEK2BAZ2BHTT | |
| SCHEMBL12393768 | 0.80 | NPC1 (0.38) | MAPTKDM4ECHEK1CHEK2BAZ2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018037230-A1 | PYRIDYL-ETHYLENEDIOXY-THIOPHENE DERIVATIVES AS TRANSPARENT CONDUCTIVE MATERIAL | UNIVERSITY OF STRATHCLYDE (GB) | 2018-03-01 | — | — | WO | disclosed |
| WO-2018037230-A1 | PYRIDYL-ETHYLENEDIOXY-THIOPHENE DERIVATIVES AS TRANSPARENT CONDUCTIVE MATERIAL | UNIVERSITY OF STRATHCLYDE (GB) | 2018-03-01 | — | — | WO | disclosed |